Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2010077317) PROTEASE INHIBITORS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/077317 International Application No.: PCT/US2009/006600
Publication Date: 08.07.2010 International Filing Date: 17.12.2009
IPC:
C07D 211/34 (2006.01) ,A61K 31/4406 (2006.01) ,A61P 31/18 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
211
Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
04
with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
06
having no double bonds between ring members or between ring members and non-ring members
08
with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
18
with substituted hydrocarbon radicals attached to ring carbon atoms
34
with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
4406
only substituted in position 3, e.g. zimeldine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12
Antivirals
14
for RNA viruses
18
for HIV
Applicants:
AMPLYX PHARMACEUTICALS, INC. [US/US]; 6256 Greenwich Drive, Suite 105 San Diego, CA 92122, US (AllExceptUS)
MUTZ, Mitchell [US/US]; US (UsOnly)
BARR, Kenneth, J. [US/US]; US (UsOnly)
GESTWICKI, Jason [US/US]; US (UsOnly)
Inventors:
MUTZ, Mitchell; US
BARR, Kenneth, J.; US
GESTWICKI, Jason; US
Agent:
RUTENBERG, Isaac, M.; Mintz, Levin, Cohn, Ferris, Glovsky And Popeo, P.C. 5 Palo Alto Square -6th Fl. 3000 El Camino Real Palo Alto, CA 94306, US
Priority Data:
61/138,42817.12.2008US
Title (EN) PROTEASE INHIBITORS
(FR) INHIBITEURS DES PROTÉASES
Abstract:
(EN) Compounds useful as protease inhibitors are provided, as are methods of use and preparation of such compounds and compositions containing such compounds. In one embodiment, the compounds are useful for inhibiting HIV protease enzymes, and are therefore useful in slowing the proliferation of HIV.
(FR) La présente invention concerne des composés utilisables en tant qu'inhibiteurs des protéases, de même que des procédés d'utilisation et de préparation desdits composés, ainsi que de compositions contenant lesdits composés. Dans un mode de réalisation, les composés sont utilisés pour l'inhibition de l'enzyme qu'est la protéase du VIH et ils se révèlent donc utiles à des fins de ralentissement de la prolifération du VIH.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
US20120041019