Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2010076519) COMPOSITION INCLUDING AN ACTIVE AGENT WITH LOW WATER SOLUBILITY
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/076519 International Application No.: PCT/FR2009/052613
Publication Date: 08.07.2010 International Filing Date: 18.12.2009
IPC:
A61K 9/50 (2006.01) ,A61K 9/51 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
50
Microcapsules
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
50
Microcapsules
51
Nanocapsules
Applicants:
FLAMEL TECHNOLOGIES [FR/FR]; 33, avenue du Docteur Georges Lévy Parc Club du Moulin à Vent F-69200 Venissieux, FR (AllExceptUS)
MEYRUEIX, Rémi [FR/FR]; FR (UsOnly)
JORDA, Rafael [FR/FR]; FR (UsOnly)
POULIQUEN, Gauthier [FR/FR]; FR (UsOnly)
CHAN, You-Ping [MU/FR]; FR (UsOnly)
BREYNE, Olivier [FR/FR]; FR (UsOnly)
Inventors:
MEYRUEIX, Rémi; FR
JORDA, Rafael; FR
POULIQUEN, Gauthier; FR
CHAN, You-Ping; FR
BREYNE, Olivier; FR
Agent:
LE COUPANEC, Pascale; Nony 3, rue de Penthièvre F-75008 Paris, FR
Priority Data:
08 5917031.12.2008FR
61/141,83431.12.2008US
Title (EN) COMPOSITION INCLUDING AN ACTIVE AGENT WITH LOW WATER SOLUBILITY
(FR) COMPOSITION COMPRENANT UN ACTIF DE FAIBLE SOLUBILITE AQUEUSE
Abstract:
(EN) The present invention relates to a composition including at least one active agent with low water solubility, said active agent being present in a form non-covalently in combination with nanoparticles made of at least one polymer POM of formula (I), and in which said active agent is present at a rate of at least 5 μmol/g of POM. The invention also relates to the use of such nanoparticles, non-covalently in combination with an active agent, with a view to increasing the water solubility of said active agent.
(FR) La présente invention concerne une composition comprenant au moins un actif de faible solubilité aqueuse, ledit actif y étant présent sous une forme associée de manière non covalente à des nanoparticules formées d'au moins un polymère POM de formule (I), et dans laquelle ledit actif est présent à raison d'au moins 5 μmol/g de POM. Elle vise en outre l'utilisation de telles nanoparticules, associées de manière non covalente à un actif, en vue d'accroître la solubilisation aqueuse dudit actif.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: French (FR)
Filing Language: French (FR)
Also published as:
EP2381931JP2012514026CN102316859CA2748713IN2692/KOLNP/2011