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1. (WO2010076400) USE OF AN ANTI-CD20 ANTIBODY FOR TREATING PRIMARY INTRAOCULAR LYMPHOMA
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/076400 International Application No.: PCT/FR2009/001349
Publication Date: 08.07.2010 International Filing Date: 26.11.2009
IPC:
A61K 39/395 (2006.01) ,A61K 35/00 (2006.01) ,C07K 16/28 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
Applicants:
LFB BIOTECHNOLOGIES [FR/FR]; ZA de Courtaboeuf 3 avenue des Tropiques F-91940 Les Ulis, FR (AllExceptUS)
FISSON, Sylvain [FR/FR]; FR (UsOnly)
FRIDMAN, Catherine [FR/FR]; FR (UsOnly)
URBAIN, Rémi [FR/FR]; FR (UsOnly)
Inventors:
FISSON, Sylvain; FR
FRIDMAN, Catherine; FR
URBAIN, Rémi; FR
Agent:
NOVAGRAAF TECHNOLOGIES; 122 Rue Edouard Vaillant F-92593 Levallois-Perret Cedex, FR
Priority Data:
08/0749630.12.2008FR
Title (EN) USE OF AN ANTI-CD20 ANTIBODY FOR TREATING PRIMARY INTRAOCULAR LYMPHOMA
(FR) UTILISATION D'UN ANTICORPS ANTI-CD20 POUR LE TRAITEMENT DU LYMPHOME INTRAOCULAIRE PRIMITIF
Abstract:
(EN) The invention relates to a monoclonal antibody directed against the CD20 antigen, in which the variable region of each of the light chains is coded by murine nucleic acid sequence SEQ ID NO: 1, the variable region of each of the heavy chains is coded by murine nucleic acid sequence SEQ ID NO: 2, and the constant regions of the light chains and of the heavy chains originate from a non-murine species, said antibody being used for treating primary intraocular lymphoma.
(FR) La présente invention se rapporte à un anticorps monoclonal dirigé contre l'antigène CD20, dont la région variable de chacune des chaînes légères est codée par la séquence d'acides nucléiques murine SEQ ID NO: 1, dont la région variable de chacune des chaînes lourdes est codée par la séquence d'acides nucléiques murine SEQ ID NO: 2, et dont les régions constantes des chaînes légères et des chaînes lourdes proviennent d'une espèce non murine, pour le traitement du lymphome intraoculaire primitif.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: French (FR)
Filing Language: French (FR)
Also published as:
EP2373336JP2012513761US20120100133FR2940616