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1. (WO2010076329) DERIVATIVES OF CYCLOSPORIN A
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/076329 International Application No.: PCT/EP2009/068017
Publication Date: 08.07.2010 International Filing Date: 30.12.2009
IPC:
C07K 7/64 (2006.01) ,A61K 38/13 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
64
Cyclic peptides containing only normal peptide links
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
12
Cyclic peptides
13
Cyclosporins
Applicants:
SCYNEXIS, INC. [US/US]; Post Office Box 12878 Research Triangle Park North Carolina 27709-2878, US (AllExceptUS)
LI, Kequiang [CN/US]; US (UsOnly)
HOUCK, David Renwick [US/US]; US (UsOnly)
OGBU, Cyprian Okwara [US/US]; US (UsOnly)
PEEL, Michael Robert [GB/US]; US (UsOnly)
SCRIBNER, Andrew William [US/US]; US (UsOnly)
Inventors:
LI, Kequiang; US
HOUCK, David Renwick; US
OGBU, Cyprian Okwara; US
PEEL, Michael Robert; US
SCRIBNER, Andrew William; US
Agent:
MURGITROYD & COMPANY; Scotland House 165-169 Scotland Street Glasgow Strathclyde G5 8PL, GB
Priority Data:
61/142,06831.12.2008US
Title (EN) DERIVATIVES OF CYCLOSPORIN A
(FR) DÉRIVÉS DE CYCLOSPORINE A
Abstract:
(EN) Disclosed herein are compounds of general formula (I) wherein A, B, R1 and R2 are as defined in the specification, and their use as pharmaceuticals.
(FR) L'invention concerne des composés de formule générale (I), dans laquelle A, B, R1 et R2 sont tels que définis dans la spécification, ainsi que leur utilisation comme produits pharmaceutiques.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
JP2012514023CN102307892CA2748389AU2009334790IN5664/DELNP/2011