Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2010075960) METHOD FOR PRODUCING RIBOFLAVIN
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/075960 International Application No.: PCT/EP2009/008987
Publication Date: 08.07.2010 International Filing Date: 15.12.2009
IPC:
C12P 25/00 (2006.01) ,C07K 14/32 (2006.01) ,C12N 15/31 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
25
Preparation of compounds containing alloxazine or isoalloxazine nucleus, e.g. riboflavin
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195
from bacteria
32
from Bacillus (G)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
31
Genes encoding microbial proteins, e.g. enterotoxins
Applicants:
DSM IP ASSETS B.V.; Het Overloon 1 NL-6411 TE Heerlen, NL (AllExceptUS)
KIRCHNER, Florian [DE/DE]; DE (UsOnly)
MAUCH, Klaus [DE/DE]; DE (UsOnly)
SCHMID, Joachim [DE/DE]; DE (UsOnly)
Inventors:
KIRCHNER, Florian; DE
MAUCH, Klaus; DE
SCHMID, Joachim; DE
Agent:
SEIBEL-THOMSEN, Nadja; DSM Nutritional Products Ltd Patent Department Wurmisweg 576 CH-4303 Kaiseraugst, CH
Priority Data:
10 2008 063 234.1 15.12.2008DE
Title (DE) VERFAHREN ZUR HERSTELLUNG VON RIBOFLAVIN
(EN) METHOD FOR PRODUCING RIBOFLAVIN
(FR) PROCÉDÉ DE PRODUCTION DE RIBOFLAVINE
Abstract:
(DE) Die Erfindung betrifft Verfahren und Mittel zur biotechnologisch fermentativen Herstellung von Riboflavin (im folgenden auch als Vitamin B2 bezeichnet) sowie Mittel zur Durchführung dieses Verfahrens, besonders eine modifizierte mikrobielle Wirtszelle mit gesteigerter Riboflavinausbeute. Die Erfindung stellt somit neue Verfahren und Mittel zur Regulation der Expression von an der Riboflavinproduktion der Wirtszelle beteiligten Enzymaktivitäten bereit.
(EN) The invention relates to a method and to means for biotechnologically fermentively producing riboflavin (also referred to in the following as vitamin B2), and to means for performing said method, in particular a modified microbial host cell having increased riboflavin production. The invention thus discloses novel methods and means for regulating the expression of enzyme activities participating in the riboflavin production of the host cell.
(FR) L'invention concerne un procédé et un moyen de production biotechnologique de riboflavine (également qualifiée ci-après de vitamine B2) par fermentation ainsi que des moyens pour mettre en œuvre ce procédé, notamment une cellule hôte microbienne modifiée au rendement en riboflavine accru. L'invention fournit ainsi un nouveau procédé et des moyens pour réguler l'expression des activités enzymatiques participant à la production de riboflavine de la cellule hôte.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: German (DE)
Filing Language: German (DE)
Also published as:
EP2358893JP2012511898US20110312026CN102245781KR1020110104955IN4290/DELNP/2011