Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2010075286) MOLECULAR ACTIVATORS OF THE Wnt/β-CATENIN PATHWAY
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/075286 International Application No.: PCT/US2009/069003
Publication Date: 01.07.2010 International Filing Date: 21.12.2009
IPC:
A01N 43/16 (2006.01) ,A61K 31/35 (2006.01)
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
43
Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
02
having rings with one or more oxygen or sulfur atoms as the only ring hetero atom
04
with one hetero atom
14
six-membered rings
16
with oxygen as the ring hetero atom
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
35
having six-membered rings with one oxygen as the only ring hetero atom
Applicants:
UNIVERSITY OF WASHINGTON [US/US]; Uw Tech Transfer 4311 11th Avenue Ne, Suite 500 Seattle, WA 98105-4608, US (AllExceptUS)
MASSACHUSETTS INSTITUTE OF TECHNOLOGY [US/US]; 77 Massachusetts Avenue Cambridge, MA 02139, US (AllExceptUS)
MOON, Randall, T. [US/US]; US (UsOnly)
BIECHELE, Travis, L. [US/US]; US (UsOnly)
CAMP, Nathan, D. [US/US]; US (UsOnly)
HAGGARTY, Stephen [CA/US]; US (UsOnly)
FASS, Daniel [US/US]; US (UsOnly)
Inventors:
MOON, Randall, T.; US
BIECHELE, Travis, L.; US
CAMP, Nathan, D.; US
HAGGARTY, Stephen; US
FASS, Daniel; US
Agent:
FITZGERALD, Mark, J.; Nixon Peabody LLP 100 Summer Street Boston, MA 02110-2131, US
Priority Data:
61/140,65524.12.2008US
Title (EN) MOLECULAR ACTIVATORS OF THE Wnt/β-CATENIN PATHWAY
(FR) INHIBITEURS MOLÉCULAIRES DE LA VOIE WNT/BÊTA-CATÉNINE
Abstract:
(EN) The present invention is directed toward a method of treating a subject for a condition mediated by aberrant Wnt/β-catenin signaling by selecting a subject with a condition mediated by aberrant Wnt/β-catenin signaling and administering to the selected subject a compound selected from the group consisting of those set forth in Table 1, Table 2, and a pharmaceutically acceptable salt thereof. A method of similarly modulating the Wnt/ β-catenin pathway in a subject is also discussed.
(FR) La présente invention concerne un procédé de traitement d'un sujet pour un état médié par une signalisation Wnt/β-caténine aberrante en sélectionnant un sujet présentant un état médié par une signalisation Wnt/β-caténine aberrante et en administrant au sujet sélectionné un composé choisi dans l'ensemble constitué des composés présentés dans le tableau 1, le tableau 2, et leurs sels pharmaceutiquement acceptables. L'invention concerne également un procédé pour moduler de manière similaire la voie Wnt/β-caténine chez un sujet.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
US20120046242