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1. (WO2010075238) HUMAN CGRP RECEPTOR BINDING PROTEINS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/075238 International Application No.: PCT/US2009/068858
Publication Date: 01.07.2010 International Filing Date: 18.12.2009
IPC:
C07K 16/28 (2006.01) ,C07K 14/72 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
705
Receptors; Cell surface antigens; Cell surface determinants
72
for hormones
Applicants:
AMGEN INC. [US/US]; One Amgen Center Drive Thousand Oaks, California 91320-1799, US (AllExceptUS)
BOONE, Thomas C. [US/US]; US (UsOnly)
BRANKOW, David W. [US/US]; US (UsOnly)
GEGG, JR., Colin V. [US/US]; US (UsOnly)
HU, Shaw-Fen Sylvia [US/US]; US (UsOnly)
KING, Chadwick T. [CA/CA]; CA (UsOnly)
LU, Hsieng Sen [US/US]; US (UsOnly)
SHI, Licheng [US/US]; US (UsOnly)
XU, Cen [US/US]; US (UsOnly)
Inventors:
BOONE, Thomas C.; US
BRANKOW, David W.; US
GEGG, JR., Colin V.; US
HU, Shaw-Fen Sylvia; US
KING, Chadwick T.; CA
LU, Hsieng Sen; US
SHI, Licheng; US
XU, Cen; US
Agent:
SHOLTZ, Charles K.; Amgen Inc. 1120 Veterans Blvd. South San Francisco, California 94080, US
Priority Data:
61/203,56923.12.2008US
61/264,62225.11.2009US
Title (EN) HUMAN CGRP RECEPTOR BINDING PROTEINS
(FR) PROTÉINES DE LIAISON AU RÉCEPTEUR CGRP HUMAIN
Abstract:
(EN) Antigen binding proteins that bind to human CGRP receptor (CGRP R) are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of CGRP R to CGRP, and are useful in a number of CGRP R related disorders, including the treatment and/or prevention of migraine headaches.
(FR) L'invention porte sur des protéines de liaison à un antigène qui se lient au récepteur CGRP humain (CGRP R). L'invention porte également sur des acides nucléiques codant pour la protéine de liaison à un antigène, sur des vecteurs et des cellules codant pour ceux-ci. Les protéines de liaison à un antigène peuvent inhiber la liaison de CGRP R à CGRP, et sont utiles dans un nombre de troubles liés à CGRP R, comprenant le traitement et/ou la prévention de maux de tête migraineux.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
DZDZP2011000498NZ593283UAa201109219IL213429SG172307EP2379594
JP2012513214CN102348722CA2746858EA201100892KR1020110106409TN2011000283
IL243784BRPI0922505AU2009330175EP3184546KR1020170061182VN30545
ID051.5384MYPI 2011002908ES2643835IN5042/DELNP/2011KR1020180043850KR1020190054181