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1. (WO2010075010) OLIGOSACCHARIDE-PROTEIN CONJUGATES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/075010 International Application No.: PCT/US2009/067775
Publication Date: 01.07.2010 International Filing Date: 11.12.2009
IPC:
A61K 47/48 (2006.01) ,A61P 3/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
48
the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
Applicants:
GENZYME CORPORATION [US/US]; 500 Kendall Street Cambridge, MA 02142, US (AllExceptUS)
PAN, Clark [US/US]; US (UsOnly)
KONOWICZ, Paul, A. [US/US]; US (UsOnly)
AVILA, Luis, Z. [US/US]; US (UsOnly)
STEFANO, James, E. [US/US]; US (UsOnly)
REARDON, Michael, R. [US/US]; US (UsOnly)
HARRAHY, John [US/US]; US (UsOnly)
ZHOU, Qun [US/US]; US (UsOnly)
YOUNG, Lauren [US/US]; US (UsOnly)
FINN, Patrick [US/US]; US (UsOnly)
ZHENG, Xiaoyang [CN/US]; US (UsOnly)
MILLER, Robert, J. [US/US]; US (UsOnly)
KUTZKO, Joseph [US/US]; US (UsOnly)
ZHU, Yunxiang [US/US]; US (UsOnly)
PATTERSON, Duncan [GB/CH]; CH (UsOnly)
PEER, Andreas [CH/CH]; CH (UsOnly)
Inventors:
PAN, Clark; US
KONOWICZ, Paul, A.; US
AVILA, Luis, Z.; US
STEFANO, James, E.; US
REARDON, Michael, R.; US
HARRAHY, John; US
ZHOU, Qun; US
YOUNG, Lauren; US
FINN, Patrick; US
ZHENG, Xiaoyang; US
MILLER, Robert, J.; US
KUTZKO, Joseph; US
ZHU, Yunxiang; US
PATTERSON, Duncan; CH
PEER, Andreas; CH
Agent:
MCDONELL, Leslie, A.; Finnegan, Henderson, Farabow, Garrett & Dunner LLP 901 New York Avenue Washington, DC 20001-4413, US
Priority Data:
61/122,85116.12.2008US
Title (EN) OLIGOSACCHARIDE-PROTEIN CONJUGATES
(FR) CONJUGUÉS OLIGOSACCHARIDE-PROTÉINE
Abstract:
(EN) Provided herein are conjugates comprising a protein and an oligosaccharide of one of Formulae I-VI. Also provided herein are pharmaceutical compositions comprising such conjugates. Further provided herein are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide- glycoprotein conjugate.
(FR) Cette invention concerne des conjugués comprenant une protéine et un oligosaccharide répondant à l'une des Formules I-VI. L'invention décrit également des compositions pharmaceutiques comprenant ces conjugués. L'invention concerne, en outre, des méthodes de traitement d'une maladie lysosomale chez un mammifère par administration d'un conjugué oligosaccharide-glycoprotéine selon l'invention.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
IL213595EP2376123EP2465542JP2012512313US20110300120CN102369023
CA2747230CN103432566MX2011006347JP2014139204EP2889043BRPI0923047
CN105879047JP2017008098IN2771/KOLNP/2011