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1. (WO2010074947) AMINO PYRAZOLE COMPOUND
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/074947 International Application No.: PCT/US2009/067056
Publication Date: 01.07.2010 International Filing Date: 08.12.2009
IPC:
C07D 487/04 (2006.01) ,A61K 31/5025 (2006.01) ,A61P 25/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
487
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
50
Pyridazines; Hydrogenated pyridazines
5025
ortho- or peri-condensed with heterocyclic ring systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
Applicants:
ELI LILLY AND COMPANY [US/US]; Lilly Corporate Center Indianapolis, Indiana 46285, US (AllExceptUS)
BURKHOLDER, Timothy, Paul [US/US]; US (UsOnly)
CLAYTON, Joshua, Ryan [US/US]; US (UsOnly)
MA, Liandong [US/US]; US (UsOnly)
Inventors:
BURKHOLDER, Timothy, Paul; US
CLAYTON, Joshua, Ryan; US
MA, Liandong; US
Agent:
MCGRAW, Elizabeth, A.; Eli Lilly and Company Patent Division P.O. Box 6288 Indianapolis, Indiana 46206-6288, US
Priority Data:
61/122,85416.12.2008US
Title (EN) AMINO PYRAZOLE COMPOUND
(FR) COMPOSÉ AMINO PYRAZOLE
Abstract:
(EN) The present invention provides amino pyrazole compounds useful in the treatment of chronic myeloproliferative disorders and various cancers, e.g., glioblastoma, breast cancer, multiple myeloma, prostate cancer, and leukemias.
(FR) La présente invention porte sur des composés amino pyrazole utiles dans le traitement de troubles myéloprolifératifs chroniques et de divers cancers, par exemple, un glioblastome, un cancer du sein, un myélome multiple, un cancer de la prostate et des leucémies.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
DZDZP2011000406UAa201107565AR074240IL213065MXMX/a/2011/006441SG172202
EP2379557US20100286139SV2011003949MA32900JP2012512158CR135/20110341
ES2396617CN102232075CA2744714EA201170831MX2011006441CO6331442
KR1020110084993TN2011000292NZ592641AU2009330503VN29934ID051.5368
MYPI 2011002704TH127998IN924/MUMNP/2011BRPI0923048