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1. (WO2010073551) C1ORF59 PEPTIDES AND VACCINES INCLUDING THE SAME
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/073551 International Application No.: PCT/JP2009/006944
Publication Date: 01.07.2010 International Filing Date: 17.12.2009
IPC:
C12N 15/00 (2006.01) ,A61K 39/00 (2006.01) ,A61P 35/00 (2006.01) ,C07K 7/06 (2006.01) ,C07K 14/705 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
06
having 5 to 11 amino acids
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
705
Receptors; Cell surface antigens; Cell surface determinants
Applicants:
ONCOTHERAPY SCIENCE, INC. [JP/JP]; 2-1, Sakado 3-chome, Takatsu-ku, Kawasaki-shi, Kanagawa 2130012, JP (AllExceptUS)
TSUNODA, Takuya [JP/JP]; JP (UsOnly)
OHSAWA, Ryuji [JP/JP]; JP (UsOnly)
YOSHIMURA, Sachiko [JP/JP]; JP (UsOnly)
WATANABE, Tomohisa [JP/JP]; JP (UsOnly)
Inventors:
TSUNODA, Takuya; JP
OHSAWA, Ryuji; JP
YOSHIMURA, Sachiko; JP
WATANABE, Tomohisa; JP
Agent:
SHIMIZU, Hatsushi; Kantetsu Tsukuba Bldg. 6F, 1-1-1, Oroshi-machi, Tsuchiura-shi, Ibaraki 3000847, JP
Priority Data:
2008-32735824.12.2008JP
61/145,91220.01.2009US
Title (EN) C1ORF59 PEPTIDES AND VACCINES INCLUDING THE SAME
(FR) PEPTIDES C1ORF59 ET VACCINS LES COMPRENANT
Abstract:
(EN) The present invention provides isolated peptides having the amino acid sequence of SEQ ID NO: 43 or immunologically active fragments thereof, which bind to HLA antigen and have cytotoxic T lymphocyte (CTL) inducibility. The present invention further provides peptides which include one, two, or several amino acid insertions, substitution or addition to the aforementioned peptides or fragments, but still have the cytotoxic T cell inducibility. Further provided are nucleic acids encoding any of these aforementioned peptides as well as pharmaceutical agents and compositions including any of the aforementioned peptides or nucleic acids. The peptides, nucleic acids, pharmaceutical agents and compositions of this invention may be used for treating cancer or tumor.
(FR) La présente invention concerne des peptides isolés présentant la séquence d'acides aminés SEQ ID NO : 43 ou des fragments immunologiquement actifs de ces peptides, qui se lient à un antigène HLA et présentent l'inductibilité du lymphocyte T cytotoxique (CTL). La présente invention comprend en outre des peptides qui comprennent une, deux, ou plusieurs insertions, substitutions ou additions d'acides aminés aux peptides ou fragments susmentionnés, mais qui présentent toujours l'inductibilité de la cellule T cytotoxique. L'invention concerne également des acides nucléiques codant pour l'un quelconque de ces peptides susmentionnés ainsi que des agents et compositions pharmaceutiques comprenant l'un quelconque des peptides ou acides nucléiques susmentionnés. Les peptides, acides nucléiques, agents et compositions pharmaceutiques de l'invention peuvent être utilisés pour traiter un cancer ou une tumeur.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
IL213318MXMX/a/2011/006755SG172374EP2382314JP2012513742US20120003253
CN102333867RU2011130796CA2747686US20140199335CN104193816MX2011006755
KR1020110117112BRPI0923402AU2009332389ID051.4251IN5235/CHENP/2011