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1. (WO2010073256) POLYMORPHS OF ZOLMITRIPTAN
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/073256 International Application No.: PCT/IN2008/000863
Publication Date: 01.07.2010 International Filing Date: 24.12.2008
IPC:
C07D 413/06 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
413
Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
02
containing two hetero rings
06
linked by a carbon chain containing only aliphatic carbon atoms
Applicants:
HETERO RESEARCH FOUNDATION [IN/IN]; Plot. No. B-80 & 81 A.P.I.E., Balanagar Hyderabad Andhrapradesh Hyderabad 500018, IN (AllExceptUS)
PARTHASARADHI REDDY, Bandi [IN/IN]; ID (UsOnly)
RATHNAKAR REDDY, Kura [IN/IN]; IN (UsOnly)
RAJI REDDY, Rapolu [IN/IN]; IN (UsOnly)
MURALIDHARA REDDY, Dasari [IN/IN]; IN (UsOnly)
SRINIVASA RAO, Thungathurthy [IN/IN]; IN (UsOnly)
Inventors:
PARTHASARADHI REDDY, Bandi; ID
RATHNAKAR REDDY, Kura; IN
RAJI REDDY, Rapolu; IN
MURALIDHARA REDDY, Dasari; IN
SRINIVASA RAO, Thungathurthy; IN
Priority Data:
Title (EN) POLYMORPHS OF ZOLMITRIPTAN
(FR) POLYMORPHES DU ZOLMITRIPTAN
Abstract:
(EN) The present invention provides a novel isopropyl acetate solvate form of zolmitriptan, and a process for its preparation thereof. The present invention also provides a process for preparation of zolmitriptan polymorph A. Thus, for example, zolmitriptan isopropanol solvate was dissolved in isopropyl acetate at 25 deg C, the contents were heated to reflux for 30 minutes and the separated solid was filtered, washed with isopropyl acetate to give zolmitriptan isopropyl acetate solvate.
(FR) La présente invention concerne une nouvelle forme de solvate d'acétate d'isopropyle du zolmitriptan et un procédé pour sa préparation. La présente invention concerne également un procédé pour la préparation du polymorphe A du zolmitriptan. Ainsi, par exemple, on a dissous du solvate d'isopropanol du zolmitriptan dans de l'acétate d'isopropyle à 25 °C, on a chauffé le contenu au reflux pendant 30 minutes, on a filtré le solide séparé puis on l'a lavé avec de l'acétate d'isopropyle pour donner du solvate d'acétate d'isopropyle du zolmitriptan.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2367819US20110263865IN8471/CHENP/2010