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1. (WO2010072405) EFFICIENT TRANSPORT INTO WHITE BLOOD CELLS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/072405 International Application No.: PCT/EP2009/009228
Publication Date: 01.07.2010 International Filing Date: 22.12.2009
IPC:
C07K 14/16 (2006.01) ,A61K 47/48 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005
from viruses
08
RNA viruses
15
Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
155
Lentiviridae, e.g. human immunodeficiency virus (HIV), visna-maedi virus, equine infectious anaemia virus
16
HIV-1
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
48
the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
Applicants:
XIGEN S.A. [CH/CH]; Rue des Terreaux 17 (4ème étage) CH-1003 Lausanne, CH (AllExceptUS)
BONNY, Christophe [CH/CH]; CH (UsOnly)
Inventors:
BONNY, Christophe; CH
Agent:
GRAF VON STOSCH, Andreas; Graf Von Stosch Patentanwaltsgesellschaft MbH Prinzregentenstrasse 22 80538 München, DE
Priority Data:
PCT/EP2008/01100322.12.2008EP
PCT/EP2009/00392702.06.2009EP
Title (EN) EFFICIENT TRANSPORT INTO WHITE BLOOD CELLS
(FR) TRANSPORT EFFICACE DANS LES GLOBULES BLANCS
Abstract:
(EN) The present invention relates to the use of specific transporter cargo conjugate molecules for the transport of a substance of interest (cargo molecule) into white blood cells. Said transporter cargo conjugate molecules may be used for the treatment, prophylaxis, attenuation and/or amelioration of a disease and/or disorder involving white blood cells. The present invention also relates to manufacture of said transporter cargo conjugate molecules, to a method of transporting a substance of interest (cargo) into a white blood cell and to a white blood cell comprising said transporter cargo conjugate molecules or fragments thereof.
(FR) La présente invention concerne l'utilisation de molécules conjuguées transporteuses/cargo spécifiques pour le transport d'une substance d'intérêt (molécule cargo) dans les globules blancs. Lesdites molécules conjuguées transporteuses/cargo peuvent être utilisées pour le traitement, la prophylaxie, l'atténuation et/ou l'amélioration d'une maladie et/ou d'un trouble impliquant les globules blancs. La présente invention concerne également la production desdites molécules conjuguées transporteuses/cargo, un procédé de transport d'une substance d'intérêt (cargo) dans un globule blanc et un globule blanc comprenant lesdites molécules conjuguées transporteuses/cargo ou un de leurs fragments.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2361259SG171707JP2012513427US20120058137CN102256999RU2011129860
CA2738989EP2947093DK2361259AU2009331921IN3246/CHENP/2011