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1. (WO2010072342) A METHOD FOR SYNTHESIS OF A RADIONUCLIDE-LABELED COMPOUND USING AN EXCHANGE RESIN
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/072342 International Application No.: PCT/EP2009/008901
Publication Date: 01.07.2010 International Filing Date: 12.12.2009
IPC:
C22B 3/42 (2006.01) ,A61K 51/00 (2006.01) ,B01D 15/16 (2006.01) ,B01J 20/26 (2006.01) ,B01J 41/00 (2006.01) ,C07B 59/00 (2006.01) ,B01J 20/281 (2006.01) ,C22B 3/24 (2006.01) ,G01N 30/32 (2006.01)
C CHEMISTRY; METALLURGY
22
METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
B
PRODUCTION OR REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
3
Extraction of metal compounds from ores or concentrates by wet processes
20
Treatment or purification of solutions, e.g. obtained by leaching
42
by ion-exchange extraction
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51
Preparations containing radioactive substances for use in therapy or testing in vivo
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
15
Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
08
Selective adsorption, e.g. chromatography
10
characterised by constructional or operational features
16
relating to the conditioning of the fluid carrier
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
J
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
20
Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
22
comprising organic material
26
Synthetic macromolecular compounds
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
J
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
41
Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
B
GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
59
Introduction of isotopes of elements into organic compounds
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
J
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
20
Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
281
Sorbents specially adapted for preparative, analytical or investigative chromatography
C CHEMISTRY; METALLURGY
22
METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
B
PRODUCTION OR REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
3
Extraction of metal compounds from ores or concentrates by wet processes
20
Treatment or purification of solutions, e.g. obtained by leaching
22
by physical processes, e.g. by filtration, by magnetic means
24
by adsorption on solid substances, e.g. by extraction with solid resins
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
30
Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography
02
Column chromatography
26
Conditioning of the fluid carrier; Flow patterns
28
Control of physical parameters of the fluid carrier
32
of pressure or speed
Applicants:
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT [DE/DE]; Mύllerstr. 178 13353 Berlin, DE (AllExceptUS)
GRAHAM, Keith [GB/DE]; DE (UsOnly)
ROTHER, Axel [DE/DE]; DE (UsOnly)
FRANCK , Dominic [CH/DE]; DE (UsOnly)
Inventors:
GRAHAM, Keith; DE
ROTHER, Axel; DE
FRANCK , Dominic; DE
Common
Representative:
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT; Patents and Licensing Müllerstrasse 178 13353 Berlin, DE
Priority Data:
08075961.6 22.12.2008EP
Title (EN) A METHOD FOR SYNTHESIS OF A RADIONUCLIDE-LABELED COMPOUND USING AN EXCHANGE RESIN
(FR) PROCÉDÉ DE SYNTHÈSE DE COMPOSÉ MARQUÉ PAR RADIONUCLIDE
Abstract:
(EN) The invention pertains to a method for eluting a radionuclide-label or a radionuclide-labeled compound using a solid phase extraction resin, to a device for performing such a method, and to a computer program for controlling such a device. Specifically, the method according to the invention enables the automated synthesis of a radionuclide-labeled compound using anion exchange resin or a reversed phase resin, and comprises the step of removing or eluting a radionuclide-label (f luorine-18, etc.) that is bound to an anion exchange resin, or a radionuclide-labeled compound that is bound to a reversed phase resin, by performing a ' 'pulsed' ' elution with an eluent.
(FR) L'invention concerne un procédé pour élution de marqueur radionuclide ou de composé marqué par radionuclide utilisant une résine d'extraction en phase solide, un dispositif permettant de réaliser un tel procédé et un programme informatique permettant de contrôler un tel dispositif.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2379757JP2012513373US20110305618CN102292461CA2747575KR1020110106895
IN5012/DELNP/2011