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1. (WO2010071582) PHARMACEUTICAL PRODUCT COMPRISING A MUSCARINIC RECEPTOR ANTAGONIST AND A SECOND ACTIVE INGREDIENT
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/071582 International Application No.: PCT/SE2009/051443
Publication Date: 24.06.2010 International Filing Date: 17.12.2009
IPC:
A61K 31/381 (2006.01) ,A61K 31/352 (2006.01) ,A61P 11/00 (2006.01) ,A61K 31/4468 (2006.01) ,A61K 31/4525 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
38
having sulfur as a ring hetero atom
381
having five-membered rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
35
having six-membered rings with one oxygen as the only ring hetero atom
352
condensed with carbocyclic rings, e.g. cannabinols, methantheline
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
445
Non-condensed piperidines, e.g. piperocaine
4468
having a nitrogen atom directly attached in position 4, e.g. clebopride, fentanyl
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
445
Non-condensed piperidines, e.g. piperocaine
4523
containing further heterocyclic ring systems
4525
containing a five-membered ring with oxygen as a ring hetero atom
Applicants:
ASTRAZENECA AB [SE/SE]; S-151 85 Södertälje, SE (AllExceptUS)
PULMAGEN THERAPEUTICS (SYNERGY) LIMITED [GB/GB]; 8/9 Spire Green Centre, Flex Meadow Harlow Essex CM19 5TR, GB (AllExceptUS)
RAY, Nicholas Charles [GB/GB]; GB (UsOnly)
VAN NEIL, Monique Bodil [NL/GB]; GB (UsOnly)
Inventors:
RAY, Nicholas Charles; GB
VAN NEIL, Monique Bodil; GB
Agent:
ASTRAZENECA INTELLECTUAL PROPERTY; AstraZeneca AB S-151 85 Södertälje, SE
Priority Data:
0823141.718.12.2008GB
Title (EN) PHARMACEUTICAL PRODUCT COMPRISING A MUSCARINIC RECEPTOR ANTAGONIST AND A SECOND ACTIVE INGREDIENT
(FR) PRODUIT PHARMACEUTIQUE COMPRENANT UN ANTAGONISTE DE RÉCEPTEUR MUSCARINIQUE ET UN SECOND PRINCIPE ACTIF
Abstract:
(EN) The invention provides a pharmaceutical product, kit or composition comprising a first active ingredient which is a selected muscarinic receptor antagonist, and a second active ingredient which is selected from a phosphodiesterase inhibitor, a modulator of chemokine receptor function, an inhibitor of kinase function, a protease inhibitor, a steroidal glucocorticoid receptor agonist, a non-steroidal glucocorticoid receptor agonist and a purinoceptor antagonist, of use in the treatment of respiratory diseases such as chronic obstructive pulmonary disease and asthma.
(FR) La présente invention concerne un produit, kit ou composition pharmaceutique incluant un premier principe actif qui est un antagoniste spécifique de récepteur muscarinique, et un second principe actif choisi parmi un inhibiteur de phosphodiestérase, un modulateur de la fonctionnalité d'un récepteur de chimiokine, un inhibiteur de la fonctionnalité des kinases, un inhibiteur de protéase, un agoniste de récepteur des glucocorticoïdes stéroïdiens, un agoniste de récepteur des glucocorticoïdes non stéroïdiens et un antagoniste de purinocepteur, pouvant être employés dans le traitement de pathologies respiratoires comme la bronchopneumopathie chronique obstructive et l'asthme.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)