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1. (WO2010067102) DIAZASPIRO [5.5] UNDECANE DERIVATIVES AND RELATED COMPOUNDS AS MUSCARINIC-RECEPTOR ANTAGONISTS AND BETA-ADRENORECEPTOR AGONISTS FOR THE TREATMENT OF PULMONARY DISORDERS
Latest bibliographic data on file with the International Bureau   
Pub. No.: WO/2010/067102 International Application No.: PCT/GB2009/051657
Publication Date: 17.06.2010 International Filing Date: 07.12.2009
IPC:
C07D 498/10 (2006.01) ,A61K 31/537 (2006.01) ,A61P 11/06 (2006.01) ,A61P 11/08 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
498
Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
02
in which the condensed system contains two hetero rings
10
Spiro-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
535
having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
537
spiro-condensed or forming part of bridged ring systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
06
Antiasthmatics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
08
Bronchodilators
Applicants:
ALCARAZ, Lilian [FR/GB]; GB (UsOnly)
KINDON, Nicholas [GB/GB]; GB (UsOnly)
STOCKS, Michael, John [GB/GB]; GB (UsOnly)
ASTRAZENECA AB [SE/SE]; S-151 85 Södertälje, SE (AllExceptUS)
PULMAGEN THERAPEUTICS (SYNERGY) LIMITED [GB/GB]; 8/9 Spire Green Centre Flex Meadow Harlow Essex CM19 5TR, GB (AllExceptUS)
Inventors:
ALCARAZ, Lilian; GB
KINDON, Nicholas; GB
STOCKS, Michael, John; GB
Agent:
BERGSTRAND, Gudmundsson; Astrazeneca Intellectual Property AstraZeneca AB S-151 85 Södertälje, SE
Priority Data:
0822437.009.12.2008GB
0913344.831.07.2009GB
Title (EN) DIAZASPIRO [5.5] UNDECANE DERIVATIVES AND RELATED COMPOUNDS AS MUSCARINIC-RECEPTOR ANTAGONISTS AND BETA-ADRENORECEPTOR AGONISTS FOR THE TREATMENT OF PULMONARY DISORDERS
(FR) DÉRIVÉS DE DIAZASPIRO[5.5]UNDÉCANE ET COMPOSÉS ASSOCIÉS UTILISÉS COMME ANTAGONISTES DES RÉCEPTEURS MUSCARINIQUES ET AGONISTES DES RÉCEPTEURS BÊTA ADRÉNERGIQUES DANS LE TRAITEMENT DES AFFECTIONS PULMONAIRES
Abstract:
(EN) Spirocyclicmorpholine-substituted amides of formula (I): processes for their preparation, pharmaceutical compositions containing them, a process for preparing pharmaceutical compositions, their use in therapy and intermediates of use in their preparation.
(FR) Cette invention concerne des amides à substitution morpholine spirocyclique de formule (I), leurs méthodes de préparation, des compositions pharmaceutiques les contenant, une méthode de préparation de ces compositions pharmaceutiques, leur utilisation dans les traitements, et les intermédiaires utilisés pour leur préparation.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)