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1. (WO2010064243) GLUTAMYL tRNA SYNTHETASE (GtS) FRAGMENTS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/064243 International Application No.: PCT/IL2009/001142
Publication Date: 10.06.2010 International Filing Date: 03.12.2009
IPC:
C12N 9/00 (2006.01) ,A61K 39/09 (2006.01) ,A61K 38/53 (2006.01) ,A61K 38/16 (2006.01) ,A61P 31/04 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
02
Bacterial antigens
09
Streptococcus
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43
Enzymes; Proenzymes; Derivatives thereof
53
Ligases (6)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04
Antibacterial agents
Applicants:
PROTEA VACCINE TECHNOLOGIES LTD. [IL/IL]; 18 Einstein Street Science Park, Kiryat Weizmann P.O. Box 4122 74140 Ness Ziona, IL (AllExceptUS)
MIZRACHI-NEBENZAHL, Yaffa [IL/IL]; IL (UsOnly)
TAL, Michael [IL/IL]; IL (UsOnly)
DAGAN, Ron [IL/IL]; IL (UsOnly)
Inventors:
MIZRACHI-NEBENZAHL, Yaffa; IL
TAL, Michael; IL
DAGAN, Ron; IL
Agent:
WEBB, Cynthia; Webb & Associates P.O. Box 2189 76121 Rehovot, IL
Priority Data:
61/119,38303.12.2008US
Title (EN) GLUTAMYL tRNA SYNTHETASE (GtS) FRAGMENTS
(FR) FRAGMENTS DE GLUTAMYL-ARNT-SYNTHÉTASE (GTS)
Abstract:
(EN) The present invention relates to polypeptide fragments, including variants and analogs, of Streptococcus pneumonia (S. pneumoniae) glutamyl tRNA synthetase (GtS) protein and to vaccines comprising such polypeptide fragments. In particular, the present invention relates to the use of such vaccines for eliciting protective immunity to S. pneumoniae.
(FR) L'invention concerne des fragments de polypeptide comprenant des variants et des analogues de la protéine glutamyl-ARNt-synthétase (GtS) de Streptococcus pneumonia (S. pneumoniae) et des vaccins comprenant ces fragments de polypeptide. L'invention concerne en particulier l'utilisation des ces vaccins pour susciter une immunité protectrice contre S. pneumoniae.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2356225IL213175JP2012510289US20110236470CN102239253CA2745205
KR1020110091560AU2009323682IN1019/MUMNP/2011BRPI0922132