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1. WO2010063996 - ANTIBACTERIAL COMPOUNDS

Publication Number WO/2010/063996
Publication Date 10.06.2010
International Application No. PCT/GB2009/002792
International Filing Date 01.12.2009
IPC
C07D 235/18 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
18with aryl radicals directly attached in position 2
C07D 401/14 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
14containing three or more hetero rings
A61K 31/4184 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
41641,3-Diazoles
4184condensed with carbocyclic rings, e.g. benzimidazoles
A61P 31/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04Antibacterial agents
CPC
A61K 31/4439
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non condensed pyridines; Hydrogenated derivatives thereof
4427containing further heterocyclic ring systems
4439containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61K 31/444
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non condensed pyridines; Hydrogenated derivatives thereof
4427containing further heterocyclic ring systems
444containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
A61P 1/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
04for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A61P 1/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
12Antidiarrhoeals
A61P 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
A61P 31/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04Antibacterial agents
Applicants
  • SUMMIT CORPORATION PLC [GB]/[GB] (AllExceptUS)
  • WILSON, Francis, Xavier [GB]/[GB] (UsOnly)
  • JOHNSON, Peter, David [GB]/[GB] (UsOnly)
  • VICKERS, Richard [GB]/[GB] (UsOnly)
  • STORER, Richard [GB]/[GB] (UsOnly)
  • WYNNE, Graham, Michael [GB]/[GB] (UsOnly)
  • ROACH, Alan, Geoffrey [GB]/[GB] (UsOnly)
  • DE MOOR, Olivier [FR]/[GB] (UsOnly)
  • DORGAN, Colin, Richard [GB]/[GB] (UsOnly)
  • DAVIS, Paul, James [GB]/[GB] (UsOnly)
Inventors
  • WILSON, Francis, Xavier
  • JOHNSON, Peter, David
  • VICKERS, Richard
  • STORER, Richard
  • WYNNE, Graham, Michael
  • ROACH, Alan, Geoffrey
  • DE MOOR, Olivier
  • DORGAN, Colin, Richard
  • DAVIS, Paul, James
Agents
  • PRICE, Vincent, Andrew
Priority Data
0821913.102.12.2008GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ANTIBACTERIAL COMPOUNDS
(FR) COMPOSÉS ANTIBACTÉRIENS
Abstract
(EN)
Disclosed are compounds of formula (I), which are of use in the treatment of bacterial diseases and infections, to compositions containing those compounds and to methods of treating bacterial diseases and infections using the compounds. In particular, the compounds are useful for the treatment of infection with, and diseases caused by, Clostridium difficile.
(FR)
L'invention se réfère à des composés représentés par la formule (I), qui sont utiles pour traiter des maladies et des infections bactériennes, à des compositions contenant ces composés et à des méthodes de traitement de maladies et d'infections bactériennes utilisant ces composés. Ces composés sont utiles, en particulier, pour traiter une infection et des maladies provoquées par Clostridium difficile.
Latest bibliographic data on file with the International Bureau