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1. (WO2010057318) DEVICES AND METHODS FOR PROVIDING CONCENTRATED BIOMOLECULE CONDENSATES TO BIOSENSING DEVICES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/057318    International Application No.:    PCT/CA2009/001709
Publication Date: 27.05.2010 International Filing Date: 24.11.2009
IPC:
G01N 1/40 (2006.01), A61L 2/16 (2006.01), A61L 2/20 (2006.01), B01D 61/14 (2006.01), B01D 61/18 (2006.01), B01D 61/20 (2006.01), B01D 63/02 (2006.01), B01D 65/02 (2006.01), C12M 1/26 (2006.01), C12M 1/34 (2006.01), C12Q 1/00 (2006.01), G01N 33/553 (2006.01), G01N 33/48 (2006.01), G01N 33/50 (2006.01), G01N 33/58 (2006.01), G01N 33/532 (2006.01), G01N 33/543 (2006.01), G01N 33/551 (2006.01), G01N 33/552 (2006.01), G01N 37/00 (2006.01), A61L 2/18 (2006.01), C12M 1/02 (2006.01), G01N 30/08 (2006.01), G01N 30/10 (2006.01), G01N 30/14 (2006.01), G01N 30/44 (2006.01), G01N 30/80 (2006.01), G01N 30/84 (2006.01), G01N 30/88 (2006.01)
Applicants: EARLY WARNING INC. [CA/CA]; 407 St. Laurent, Suite 500 Montreal, Quebec H2Y 2Y5 (CA) (For All Designated States Except US).
GORDON, Neil [CA/CA]; (CA) (For US Only).
PALMATEER, Garry [CA/CA]; (CA) (For US Only).
GELB, George [CA/CA]; (CA) (For US Only)
Inventors: GORDON, Neil; (CA).
PALMATEER, Garry; (CA).
GELB, George; (CA)
Agent: ROBIC; CENTRE CDP CAPITAL 1001, Square-Victoria, Bloc E - 8th Floor Montreal, Quebec H2Z 2B7 (CA)
Priority Data:
61/117,337 24.11.2008 US
Title (EN) DEVICES AND METHODS FOR PROVIDING CONCENTRATED BIOMOLECULE CONDENSATES TO BIOSENSING DEVICES
(FR) DISPOSITIFS ET PROCÉDÉS POUR DISTRIBUER DES CONDENSATS DE BIOMOLÉCULE CONCENTRÉS À DES DISPOSITIFS DE BIODÉTECTION
Abstract: front page image
(EN)Condensing devices and methods for providing a concentrated biomolecule condensate to one or more biosensing devices are provided. The concentrated biomolecule condensate is obtained from a fluid sample which potentially contains traces of one or more target biomolecules. The fluid sample is first separated into a filtered liquid and a retentate biomolecule condensate. A novel filtering module is provided for this purpose. The target biomolecules in the retentate biomolecule condensate are further separated from unwanted materials using magnetic beads coated with antibodies of the target biomolecules. The beaded biomolecule condensate obtained thereby is processed to extract constituents of the target biomolecules, thereby obtaining the concentrated biomolecule condensate, which is distributed to a biosensing device.
(FR)L'invention porte sur des dispositifs et des procédés de condensation pour distribuer un condensat de biomolécule concentré à un ou à plusieurs dispositifs de biodétection. Le condensat de biomolécule concentré est obtenu d'un échantillon fluide qui contient potentiellement des traces d’une ou de plusieurs biomolécules cibles. L'échantillon fluide est tout d'abord séparé en un liquide filtré et en un rétentat de condensat de biomolécule. Un nouveau module de filtrage est proposé à cette fin. Les biomolécules cibles dans le rétentat de condensat de biomolécule sont en outre séparées de matières non désirées à l'aide de billes magnétiques revêtues des anticorps des biomolécules cibles. Le condensat de biomolécule sur billes, ainsi obtenu, est traité pour extraire des constituants des biomolécules cibles, obtenant ainsi le condensat de biomolécule concentré qui est distribué à un dispositif de biodétection.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)