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1. WO2010045421 - PHOTOACOUSTIC IMAGING USING A VERSATILE ACOUSTIC LENS

Publication Number WO/2010/045421
Publication Date 22.04.2010
International Application No. PCT/US2009/060774
International Filing Date 15.10.2009
IPC
A61B 8/08 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
8Diagnosis using ultrasonic, sonic or infrasonic waves
08Detecting organic movements or changes, e.g. tumours, cysts, swellings
CPC
A61B 5/0084
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
0059using light, e.g. diagnosis by transillumination, diascopy, fluorescence
0082adapted for particular medical purposes
0084for introduction into the body, e.g. by catheters
A61B 5/0095
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
0093Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
0095by applying light and detecting acoustic waves, i.e. photoacoustic measurements
A61B 5/4887
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
48Other medical applications
4887Locating particular structures in or on the body
A61B 8/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
8Diagnosis using ultrasonic, sonic or infrasonic waves
08Detecting organic movements or changes, e.g. tumours, cysts, swellings
A61B 8/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
8Diagnosis using ultrasonic, sonic or infrasonic waves
12in body cavities or body tracts, e.g. by using catheters
G01N 29/221
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
29Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
22Details ; , e.g. general constructional or apparatus details
221Arrangements for directing or focusing the acoustical waves
Applicants
  • UNIVERSITY OF ROCHESTER [US]/[US] (AllExceptUS)
  • ROCHESTER INSTITUTE OF TECHNOLOGY [US]/[US] (AllExceptUS)
  • DOGRA, Vikram S. [US]/[US] (UsOnly)
  • RAO, Navalgund, A. H. K. [US]/[US] (UsOnly)
  • KNOX, Wayne H. [US]/[US] (UsOnly)
Inventors
  • DOGRA, Vikram S.
  • RAO, Navalgund, A. H. K.
  • KNOX, Wayne H.
Agents
  • GREENBAUM, Michael
Priority Data
61/105,59015.10.2008US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PHOTOACOUSTIC IMAGING USING A VERSATILE ACOUSTIC LENS
(FR) IMAGERIE PHOTOACOUSTIQUE À L'AIDE D'UNE LENTILLE ACOUSTIQUE POLYVALENTE
Abstract
(EN)
To image various soft tissues in the body using pulsed laser optical excitation delivered through a multi-mode optical fiber to create photoacoustic impulses, and then image the generated photoacoustic impulses with an acoustic detector array, a probe includes either a mirror and an acoustic lens or a special acoustic lens of variable focal length and magnification that can operate in a liquid environment that is aberration-corrected to a sufficient degree that high resolution images can be obtained with lateral as well as depth resolution.
(FR)
Selon la présente invention, pour former des images de divers tissus mous dans le corps à l'aide d'une excitation optique laser pulsée délivrée par une fibre optique multimodale afin de créer des impulsions photoacoustiques, puis pour former les images des impulsions photoacoustiques générées avec une matrice de capteurs acoustiques, une sonde comprend soit un miroir et une lentille acoustique, soit une lentille acoustique spéciale de longueur focale variable et d'agrandissement variable qui peuvent fonctionner dans un environnement liquide qui est corrigé en aberration à un degré suffisant pour que des images haute résolution puissent être obtenues avec une résolution latérale ainsi qu'en profondeur.
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