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1. (WO2010034037) SALIVARY METABOLIC BIOMARKERS FOR HUMAN ORAL CANCER DETECTION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/034037    International Application No.:    PCT/US2009/064974
Publication Date: 25.03.2010 International Filing Date: 18.11.2009
IPC:
G01N 33/574 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [--/US]; Office of Technology Transfer 1111 Franklin St. 12th Floor Oakland, California 94607-5200 (US) (For All Designated States Except US).
KEIO UNIVERSITY [--/JP]; 2-15-45, Mita, Minato-ku Tokyo 108-8345 (JP) (For All Designated States Except US).
WONG, David [US/US]; (US) (For US Only).
TOMITA, Masaru [JP/JP]; (JP) (For US Only).
SUGIMOTO, Masahiro [JP/JP]; (JP) (For US Only).
HIRAYAMA, Akiyoshi [JP/JP]; (JP) (For US Only).
SOGA, Tomoyoshi [JP/JP]; (JP) (For US Only)
Inventors: WONG, David; (US).
TOMITA, Masaru; (JP).
SUGIMOTO, Masahiro; (JP).
HIRAYAMA, Akiyoshi; (JP).
SOGA, Tomoyoshi; (JP)
Agent: ARMSTRONG, Joel; Oliff & Berridge, PLC 277 South Washington Street Alexandria, Virginia 22314 (US)
Priority Data:
61/099,110 22.09.2008 US
12/585,598 18.09.2009 US
Title (EN) SALIVARY METABOLIC BIOMARKERS FOR HUMAN ORAL CANCER DETECTION
(FR) BIOMARQUEURS MÉTABOLIQUES SALIVAIRES POUR LA DÉTECTION D'UN CANCER BUCCAL HUMAIN
Abstract: front page image
(EN)The present invention provides a novel oral cancer and periodontal disease salivary metabolome for use in the diagnosis or for providing a prognosis for oral cancer and periodontal disease in an individual. The present invention also provides novel methods of diagnosing or providing a prognosis for oral cancer or periodontal disease by detecting metabolites found in the saliva of an individual. Finally, the present invention provides kits for the detection of salivary metabolites useful in the diagnosis or prognosis of oral cancer and periodontal disease in an individual.
(FR)La présente invention concerne un nouveau métabolome salivaire du cancer buccal et d'une maladie parodontale destiné à être utilisé dans le diagnostic d’un cancer buccal et d’une maladie parodontale chez un individu ou pour fournir un pronostic de ceux-ci. L'invention concerne aussi de nouveaux procédés de diagnostic de cancer buccal et de maladie parodontale ou pour fournir un pronostic de cancer buccal ou de maladie parodontale en détectant les métabolites trouvés dans la salive d'un individu. Enfin, l'invention concerne des kits destinés à la détection de métabolites salivaires utiles dans le diagnostic ou le pronostic d'un cancer buccal et d'une maladie parodontale chez un individu.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)