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1. WO2010034028 - PEPTIDOMIMETIC MARCROCYCLES

Publication Number WO/2010/034028
Publication Date 25.03.2010
International Application No. PCT/US2009/057927
International Filing Date 22.09.2009
IPC
C07K 7/56 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
50Cyclic peptides containing at least one abnormal peptide link
54with at least one abnormal peptide link in the ring
56the cyclisation not occurring through 2,4-diamino-butanoic acid
C07K 14/47 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
CPC
A61P 27/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27Drugs for disorders of the senses
02Ophthalmic agents
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
C07K 14/4702
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
4701not used
4702Regulators; Modulating activity
C07K 7/56
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
50Cyclic peptides containing at least one abnormal peptide link
54with at least one abnormal peptide link in the ring
56the cyclisation not occurring through 2,4-diamino-butanoic acid
Applicants
  • AILERON THERAPEUTICS, INC. [US]/[US] (AllExceptUS)
  • NASH, Huw, M. [US]/[US] (UsOnly)
  • KAPELLER-LIBERMANN, Rosana [US]/[US] (UsOnly)
  • HAN, Jia-wen [US]/[US] (UsOnly)
  • SAWYER, Tomi, K. [US]/[US] (UsOnly)
  • NOEHRE, Justin [US]/[US] (UsOnly)
Inventors
  • NASH, Huw, M.
  • KAPELLER-LIBERMANN, Rosana
  • HAN, Jia-wen
  • SAWYER, Tomi, K.
  • NOEHRE, Justin
Agents
  • ORBAI, Lucian
Priority Data
61/099,17222.09.2008US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) PEPTIDOMIMETIC MARCROCYCLES
(FR) MACROCYCLES PEPTIDOMIMÉTIQUES
Abstract
(EN) The present invention provides novel peptidomimetic macrocycles and methods of using such macrocycles for the treatment of disease.
(FR) La présente invention concerne de nouveaux macrocycles peptidomimétiques et des procédés d’utilisation de tels macrocycles pour le traitement d’une maladie.
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