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Machine translation
1. (WO2010034007) METHODS FOR DETECTING A MYCOBACTERIUM TUBERCULOSIS INFECTION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/034007    International Application No.:    PCT/US2009/057891
Publication Date: 25.03.2010 International Filing Date: 22.09.2009
IPC:
G01N 33/569 (2006.01)
Applicants: OREGON HEALTH & SCIENCE UNIVERSITY [US/US]; Office of Technology and Research Collaborations 2525 SW First Avenue, Suite #120 Portland, OR 97201 (US) (For All Designated States Except US).
THE GOVERNMENT OF THE UNITED STATES OF AMERICA d.b.a. THE DEPARTMENT OF VETERANS AFFAIRS [US/US]; office of the General Counsel 810 Vermont Avenue N.W. Washington, DC 20420 (US) (For All Designated States Except US).
LEWINSOHN, Deborah, A. [US/US]; (US) (For US Only).
LEWINSOHN, David, M. [US/US]; (US) (For US Only)
Inventors: LEWINSOHN, Deborah, A.; (US).
LEWINSOHN, David, M.; (US)
Agent: SIEGEL, Susan, Alpert; Klarquist Sparkman, LLP One World Trade Center, Suite 1600 121 SW Salmon Street Portland, OR 97204 (US)
Priority Data:
61/099,162 22.09.2008 US
Title (EN) METHODS FOR DETECTING A MYCOBACTERIUM TUBERCULOSIS INFECTION
(FR) MÉTHODES PERMETTANT DE DÉTECTER UNE INFECTION PAR LE BACILLE DE KOCH
Abstract: front page image
(EN)Methods for detecting an infection with Mycobacterium tuberculosis (Mtb) in a subject are disclosed, wherein the subject is a child, a subject with a latent Mycobacterium tuberculosis infection. Method are also disclose for detecting an extra-pulmonary Mycobacterium tuberculosis infection in a subject. The methods include detecting the presence of CD8+T cells that specifically recognize an Mtb polypeptide. The methods include in vitro assays for detecting the presence of CD8+T cells in a biological sample.
(FR)L’invention concerne des méthodes permettant de détecter une infection par le bacille de Koch (Mtb) chez un sujet, le sujet étant un enfant présentant une infection latente par le bacille de Koch. Des méthodes permettant de détecter une infection extra-pulmonaire par le bacille de Koch chez un sujet sont également décrites. Les méthodes comprennent la détection de la présence de lymphocytes T CD8+ qui reconnaissent spécifiquement un polypeptide Mtb. Les méthodes comprennent des essais in vitro permettant de détecter la présence de lymphocytes T CD8+ dans un échantillon biologique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)