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1. (WO2010033977) MULTIHETEROARYL COMPOUNDS AS INHIBITORS OF H-PGDS AND THEIR USE FOR TREATING PROSTAGLANDIN D2 MEDIATED DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/033977    International Application No.:    PCT/US2009/057813
Publication Date: 25.03.2010 International Filing Date: 22.09.2009
IPC:
C07D 403/14 (2006.01), C07D 401/14 (2006.01), C07D 401/04 (2006.01), C07D 403/04 (2006.01), C07D 417/14 (2006.01), A61K 31/167 (2006.01), A61K 31/425 (2006.01), A61P 11/00 (2006.01)
Applicants: CAYMAN CHEMICAL COMPANY [US/US]; 1180 N. Ellsworth Road Ann Arbor, MI 48108 (US) (For All Designated States Except US).
ENDRES, Gregory, W. [US/US]; (US) (For US Only).
LEE, Pil, Heui [US/US]; (US) (For US Only).
OLSON, Kirk, Lang [US/US]; (US) (For US Only).
KRAMER, James, Bernard [US/US]; (US) (For US Only).
CISKE, Fred, Lawrence [US/US]; (US) (For US Only).
BARRETT, Stephen, Douglas [US/US]; (US) (For US Only)
Inventors: ENDRES, Gregory, W.; (US).
LEE, Pil, Heui; (US).
OLSON, Kirk, Lang; (US).
KRAMER, James, Bernard; (US).
CISKE, Fred, Lawrence; (US).
BARRETT, Stephen, Douglas; (US)
Agent: HAYS, Steven, W.; (US)
Priority Data:
61/098,942 22.09.2008 US
Title (EN) MULTIHETEROARYL COMPOUNDS AS INHIBITORS OF H-PGDS AND THEIR USE FOR TREATING PROSTAGLANDIN D2 MEDIATED DISEASES
(FR) COMPOSES MULTIHETEROARYLES SERVANT D'INHIBITEURS DE LA H-PGDS, AINSI QUE LEUR UTILISATION DANS LE TRAITEMENT DES MALADIES INDUITES PAR LA PROSTAGLANDINE D2
Abstract: front page image
(EN)Multiheteroaryl compounds, their preparation, pharmaceutical compositions comprising these compounds, and their pharmaceutical use in the prevention and treatment of prostaglandin D2 mediated diseases and conditions that may be modulated by the inhibition of hematopoietic prostaglandin D synthase (H-PGDS).
(FR)L'invention concerne des composés multihétéroaryles, leur préparation, des compositions pharmaceutiques les contenant, ainsi que leur utilisation pharmaceutique dans la prévention et le traitement des maladies et des affections induites par la prostaglandine D2 et pouvant être modulées par l'inhibition de la prostaglandine D synthase hématopoïétique (H-PGDS).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)