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1. (WO2010033733) FOLATE RECEPTOR BINDING CONJUGATES OF ANTIFOLATES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/033733    International Application No.:    PCT/US2009/057363
Publication Date: 25.03.2010 International Filing Date: 17.09.2009
IPC:
A61K 31/517 (2006.01), A61P 11/06 (2006.01)
Applicants: ENDOCYTE, INC. [US/US]; 3000 Kent Avenue West Lafayette, IN 47906 (US) (For All Designated States Except US).
LEAMON, Christopher, Paul [US/US]; (US) (For US Only).
VLAHOV, Iontcho, Radoslavov [US/US]; (US) (For US Only).
LOW, Philip, Stewart [US/US]; (US) (For US Only)
Inventors: LEAMON, Christopher, Paul; (US).
VLAHOV, Iontcho, Radoslavov; (US).
LOW, Philip, Stewart; (US)
Agent: BALL, Rebecca, L.; (US)
Priority Data:
61/097,655 17.09.2008 US
Title (EN) FOLATE RECEPTOR BINDING CONJUGATES OF ANTIFOLATES
(FR) CONJUGUÉS D'ANTIFOLATES LIANT LE RÉCEPTEUR DE FOLATE
Abstract: front page image
(EN)Conjugates of antifolates, releasable linkers, and drugs, and pharmaceutical compositions containing them are described. The conjugates are useful for treating diseases arising from pathogenic cell populations. Methods for treating such diseases are also described.
(FR)L'invention concerne des conjugués d'antifolates, de lieurs libérables, et de médicaments, et des compositions pharmaceutiques les contenant. Les conjugués sont utiles pour traiter des maladies attribuables à des populations de cellules pathogènes. L'invention concerne également des procédés de traitement de ces maladies.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)