WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2010033617) STAPLED PEPTIDES AND METHOD OF SYNTHESIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/033617    International Application No.:    PCT/US2009/057189
Publication Date: 25.03.2010 International Filing Date: 16.09.2009
IPC:
A61K 38/00 (2006.01), B01J 19/12 (2006.01), C07D 213/61 (2006.01)
Applicants: THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK [US/US]; STOR Intellectual Property Division UB Technology Incubator, Suite 111 Amherst, NY 14228-2567 (US) (For All Designated States Except US).
LIN, Qing [CN/US]; (US) (For US Only).
MADDEN, Michael [US/US]; (US) (For US Only).
RIVERA VERA, Claudia, Ivette [MX/US]; (US) (For US Only)
Inventors: LIN, Qing; (US).
MADDEN, Michael; (US).
RIVERA VERA, Claudia, Ivette; (US)
Agent: ROMAN, Paul, J.; Hodgson Russ LLP The Guaranty Building 140 Pearl Street, Suite 100 Buffalo, NY 14202-4040 (US)
Priority Data:
61/097,357 16.09.2008 US
Title (EN) STAPLED PEPTIDES AND METHOD OF SYNTHESIS
(FR) PEPTIDES AGRAFÉS ET PROCÉDÉ DE SYNTHÈSE
Abstract: front page image
(EN)A method for preparing stapled peptides. The stapled peptides, including helical stapled peptides, are prepared according to a photochemically-based method, a [3+2] cycloaddition reaction. The helical stapled peptides exhibit increased helicity, thermal stability and cell permeability.
(FR)L'invention concerne un procédé de préparation de peptides agrafés. Les peptides agrafés, notamment les peptides hélicoïdaux agrafés, sont préparés conformément à un procédé basé sur la photochimie, une réaction de cycloaddition [3+2]. Les peptides hélicoïdaux agrafés présentent une hélicité, une stabilité thermique et une perméabilisation cellulaire accrues.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)