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Machine translation
1. (WO2010033294) SHORT-FORM HUMAN MD-2 AS A NEGATIVE REGULATOR OF TOLL-LIKE RECEPTOR 4 SIGNALING
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/033294    International Application No.:    PCT/US2009/050317
Publication Date: 25.03.2010 International Filing Date: 10.07.2009
IPC:
C07K 14/00 (2006.01), A61K 38/00 (2006.01)
Applicants: CEDARS-SINAI MEDICAL CENTER [US/US]; 8700 Beverly Boulevard Los Angeles, CA 90048 (US) (For All Designated States Except US).
ARDITI, Moshe [US/US]; (US) (For US Only).
GRAY, Pearl, S. [IE/US]; (US) (For US Only)
Inventors: ARDITI, Moshe; (US).
GRAY, Pearl, S.; (US)
Agent: TRUONG, Linda; (US)
Priority Data:
61/098,861 22.09.2008 US
Title (EN) SHORT-FORM HUMAN MD-2 AS A NEGATIVE REGULATOR OF TOLL-LIKE RECEPTOR 4 SIGNALING
(FR) MD-2 HUMAINE SOUS SA FORME COURTE UTILISÉE COMME RÉGULATEUR NÉGATIF DE LA SIGNALISATION PAR LE RÉCEPTEUR DE TYPE TOLL-4
Abstract: front page image
(EN)The present invention is based on a novel, alternatively spliced human isoform of MD-2 (MD-2s). In various embodiments, the invention relates to methods and kits for preventing, reducing the likelihood of developing and/or treating various conditions using MD-2s. The invention also describes methods of determining the risk of a subject to various conditions.
(FR)La présente invention concerne une nouvelle isoforme humaine alternativement épissée de MD-2 (MD-2s). Dans divers modes de réalisation, l'invention concerne des procédés et des kits destinés à prévenir, à réduire le risque de développer et/ou à traiter diverses pathologies au moyen de MD-2s. L’invention concerne également des procédés de détermination du risque pour un sujet de développer diverses pathologies.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)