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1. (WO2010033236) METHODS AND COMPOSITIONS FOR TREATING BACTERIAL INFECTIONS BY INHIBITING QUORUM SENSING
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/033236    International Application No.:    PCT/US2009/005229
Publication Date: 25.03.2010 International Filing Date: 18.09.2009
IPC:
A01N 43/36 (2006.01), A61K 31/40 (2006.01)
Applicants: ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY [US/US]; 1300 Morris Park Avenue Bronx, NY 10461 (US) (For All Designated States Except US).
SCHRAMM, Vern, L. [US/US]; (US) (For US Only)
Inventors: SCHRAMM, Vern, L.; (US)
Agent: MILLER, Alan, D.; Amster, Rothstein & Ebenstein LLP 90 Park Avenue New York, NY 10016 (US)
Priority Data:
61/192,796 22.09.2008 US
Title (EN) METHODS AND COMPOSITIONS FOR TREATING BACTERIAL INFECTIONS BY INHIBITING QUORUM SENSING
(FR) PROCÉDÉS ET COMPOSITIONS POUR LE TRAITEMENT D'INFECTIONS BACTÉRIENNES PAR L'INHIBITION DE LA DÉTECTION DU QUORUM
Abstract: front page image
(EN)The present invention provides methods for treating bacterial infections in a subject comprising administering to the subject a sub-growth inhibiting amount of a 5'-Methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) inhibitor. The present invention further provides pharmaceutical compositions comprising a sub-bacterial-growth inhibiting amount of a 5'-Methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) inhibitor and a pharmaceutically acceptable carrier.
(FR)La présente invention concerne des procédés pour le traitement d'infections bactériennes chez un sujet comprenant l'administration au sujet d'une quantité inhibitrice de sous-croissance d'un inhibiteur de la 5'-méthylthioadénosine/S-adénosyl homocystéine nucléosidase (MTAN). La présente invention concerne également des compositions pharmaceutiques comportant une une quantité inhibitrice de sous-croissance bactérienne d'un inhibiteur de la 5'-méthylthioadénosine/S-adénosyl homocystéine nucléosidase (MTAN) et un support pharmaceutiquement acceptable.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)