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1. (WO2010033221) POLYMER CONJUGATES OF PROTEGRIN PEPTIDES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/033221    International Application No.:    PCT/US2009/005210
Publication Date: 25.03.2010 International Filing Date: 17.09.2009
IPC:
A61K 47/48 (2006.01), C07K 7/08 (2006.01), A61P 31/04 (2006.01)
Applicants: NEKTAR THERAPEUTICS [US/US]; 201 Industrial Road San Carlos, California 94070 (US) (For All Designated States Except US).
WANG, Yujun [CN/US]; (US) (For US Only).
MOSKOWITZ, Haim [US/US]; (US) (For US Only).
LIU, Xiaofeng [CN/US]; (US) (For US Only).
ROCZNIAK, Steven O. [US/US]; (US) (For US Only).
BOSSARD, Mary J. [US/US]; (US) (For US Only)
Inventors: WANG, Yujun; (US).
MOSKOWITZ, Haim; (US).
LIU, Xiaofeng; (US).
ROCZNIAK, Steven O.; (US).
BOSSARD, Mary J.; (US)
Agent: DESAI, Naishadh; (US)
Priority Data:
61/192,586 19.09.2008 US
Title (EN) POLYMER CONJUGATES OF PROTEGRIN PEPTIDES
(FR) CONJUGUÉS POLYMÈRES DE PEPTIDES DE PROTÉGRINE
Abstract: front page image
(EN)The invention provides protegrin that are chemically modified by covalent attachment of a water soluble oligomer. A conjugate of the invention has enhanced half-life and/or reduced clearance.
(FR)La présente invention concerne une protégrine qui est chimiquement modifiée par liaison covalente d'un oligomère soluble dans l'eau. Un conjugué de l'invention présente une demi-vie améliorée et/ou une clairance réduite.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)