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1. (WO2010032771) AMINO ACID DERIVATIVE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/032771    International Application No.:    PCT/JP2009/066217
Publication Date: 25.03.2010 International Filing Date: 17.09.2009
IPC:
C07C 233/49 (2006.01), A61K 31/198 (2006.01), A61K 31/216 (2006.01), A61K 31/27 (2006.01), A61K 31/277 (2006.01), A61K 31/343 (2006.01), A61K 31/37 (2006.01), A61K 31/4015 (2006.01), A61K 31/405 (2006.01), A61P 29/02 (2006.01), C07C 235/34 (2006.01), C07C 255/57 (2006.01), C07C 279/14 (2006.01), C07C 323/59 (2006.01), C07D 207/452 (2006.01), C07D 209/20 (2006.01), C07D 307/85 (2006.01), C07D 311/12 (2006.01), C07D 405/06 (2006.01)
Applicants: NIPPON ZOKI PHARMACEUTICAL CO., LTD. [JP/JP]; 1-2, Hiranomachi 2-chome, Chuo-ku, Osaka-shi, Osaka 5410046 (JP) (For All Designated States Except US).
OOKUBO, Tomohiro [JP/JP]; (JP) (For US Only).
NAKAMURA, Ko [JP/JP]; (JP) (For US Only).
NANBA, Hiroyoshi [JP/JP]; (JP) (For US Only).
YOSHIDA, Hiroyuki [JP/JP]; (JP) (For US Only).
NAKAZAWA, Yoshitaka [JP/JP]; (JP) (For US Only)
Inventors: OOKUBO, Tomohiro; (JP).
NAKAMURA, Ko; (JP).
NANBA, Hiroyoshi; (JP).
YOSHIDA, Hiroyuki; (JP).
NAKAZAWA, Yoshitaka; (JP)
Agent: FUJII, Ikuro; (JP)
Priority Data:
2008-239282 18.09.2008 JP
Title (EN) AMINO ACID DERIVATIVE
(FR) DÉRIVÉ D'ACIDE AMINÉ
(JA) アミノ酸誘導体
Abstract: front page image
(EN)Disclosed is a novel amino acid derivative having excellent analgesic activity. The amino acid derivative is a novel compound which exhibits excellent analgesic activity not only with respect to nociceptive pain model animals, but also with respect to neuropathic pain model animals, and is extremely useful as a medical agent for the treatment of various painful conditions that exhibit acute or chronic pain or neuropathic pain.
(FR)L'invention concerne un nouveau dérivé d'acide aminé présentant une excellente activité analgésique. Il s'agit d'un nouveau composé présentant une excellente activité analgésique sur la douleur nociceptive d'animaux modèles, mais aussi sur leur douleur neuropathique, et qui s'avère extrêmement utile comme agent médical de traitement de différentes algies, aigues, chroniques ou neuropathiques.
(JA)本発明は優れた鎮痛作用を有する新規なアミノ酸誘導体を提供する。本発明アミノ酸誘導体は侵害受容性疼痛モデル動物だけでなく、神経因性疼痛モデル動物に対しても優れた鎮痛作用を示す新規化合物であり、急性又は慢性の疼痛や神経因性疼痛を呈する種々の疼痛性疾患を治療するための薬剤として非常に有用である。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)