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Pub. No.:    WO/2010/032771    International Application No.:    PCT/JP2009/066217
Publication Date: 25.03.2010 International Filing Date: 17.09.2009
C07C 233/49 (2006.01), A61K 31/198 (2006.01), A61K 31/216 (2006.01), A61K 31/27 (2006.01), A61K 31/277 (2006.01), A61K 31/343 (2006.01), A61K 31/37 (2006.01), A61K 31/4015 (2006.01), A61K 31/405 (2006.01), A61P 29/02 (2006.01), C07C 235/34 (2006.01), C07C 255/57 (2006.01), C07C 279/14 (2006.01), C07C 323/59 (2006.01), C07D 207/452 (2006.01), C07D 209/20 (2006.01), C07D 307/85 (2006.01), C07D 311/12 (2006.01), C07D 405/06 (2006.01)
Applicants: NIPPON ZOKI PHARMACEUTICAL CO., LTD. [JP/JP]; 1-2, Hiranomachi 2-chome, Chuo-ku, Osaka-shi, Osaka 5410046 (JP) (For All Designated States Except US).
OOKUBO, Tomohiro [JP/JP]; (JP) (For US Only).
NAKAMURA, Ko [JP/JP]; (JP) (For US Only).
NANBA, Hiroyoshi [JP/JP]; (JP) (For US Only).
YOSHIDA, Hiroyuki [JP/JP]; (JP) (For US Only).
NAKAZAWA, Yoshitaka [JP/JP]; (JP) (For US Only)
Inventors: OOKUBO, Tomohiro; (JP).
NANBA, Hiroyoshi; (JP).
YOSHIDA, Hiroyuki; (JP).
NAKAZAWA, Yoshitaka; (JP)
Agent: FUJII, Ikuro; (JP)
Priority Data:
2008-239282 18.09.2008 JP
(JA) アミノ酸誘導体
Abstract: front page image
(EN)Disclosed is a novel amino acid derivative having excellent analgesic activity. The amino acid derivative is a novel compound which exhibits excellent analgesic activity not only with respect to nociceptive pain model animals, but also with respect to neuropathic pain model animals, and is extremely useful as a medical agent for the treatment of various painful conditions that exhibit acute or chronic pain or neuropathic pain.
(FR)L'invention concerne un nouveau dérivé d'acide aminé présentant une excellente activité analgésique. Il s'agit d'un nouveau composé présentant une excellente activité analgésique sur la douleur nociceptive d'animaux modèles, mais aussi sur leur douleur neuropathique, et qui s'avère extrêmement utile comme agent médical de traitement de différentes algies, aigues, chroniques ou neuropathiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)