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Machine translation
1. (WO2010032261) PROCESS FOR PREPARATION OF BOSENTAN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/032261    International Application No.:    PCT/IN2009/000443
Publication Date: 25.03.2010 International Filing Date: 07.08.2009
Chapter 2 Demand Filed:    08.03.2010    
IPC:
C07D 239/69 (2006.01), C07D 239/38 (2006.01), C07D 239/54 (2006.01)
Applicants: CADILA HEALTHCARE LIMITED [IN/IN]; Zydus Tower Satellite Cross Roads Ahmedabad 380 015 Gujarat (IN) (For All Designated States Except US).
SATA, Kaushilk [IN/IN]; (IN) (For US Only).
PANDEY, Bipin [IN/IN]; (IN) (For US Only)
Inventors: SATA, Kaushilk; (IN).
PANDEY, Bipin; (IN)
Agent: SUBRAMANIAM, Hariharan; Subramaniam, Nataraj & Associates E-556, Greater Kailash-ll New DeIhi 110 048 (IN)
Priority Data:
1705/MUM/2008 12.08.2008 IN
537/MUM/2009 12.03.2009 IN
Title (EN) PROCESS FOR PREPARATION OF BOSENTAN
(FR) PROCÉDÉ POUR LA PRÉPARATION DE BOSENTAN
Abstract: front page image
(EN)The present invention provides improved processes for preparing Bosentan. The present invention provides novel intermediates like 4,6-dihydroxy-5-(2-methoxy phenoxy)[2,2'] bipyrimidine of formula (II) and N-(6-Chloro-5-(2- ethoxyphenoxy)[2,2'-bipyrimidinyl]-4-t-butyl benzenesulfonamide cesium salt and process for preparation thereof. The invention also disclosed novel polymorphic form of the intermediates.
(FR)La présente invention concerne des procédés améliorés pour la préparation de bosentan. La présente invention concerne également de nouveaux intermédiaires tels que 4,6-dihydroxy-5-(2-méthoxy phénoxy)[2,2'] bipyrimidine de formule (II) et le sel de césium de N-(6-Chloro-5-(2- éthoxyphénoxy)[2,2'-bipyrimidinyl]-4-t-butyl benzènesulfonamide et leur procédé de préparation. L’invention concerne en outre une nouvelle forme polymorphe des intermédiaires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)