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1. (WO2010032254) INDUSTRIAL PROCESS FOR CIS(+M-2-R(DIMETHYLAMINO)-METHYL-1-(3- METHOXYPHENYL) CYCLOHEXANOL HYDROCHLORIDE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/032254    International Application No.:    PCT/IN2008/000763
Publication Date: 25.03.2010 International Filing Date: 10.11.2008
IPC:
C07C 213/00 (2006.01), C07C 213/10 (2006.01), C07C 217/74 (2006.01)
Applicants: KAMUD DRUGS PVT . LTD . [IN/IN]; 306/307 , "B " Wing, Shiv Chamber , Plot No . 21 , Sector 11 , CBD Belapur , 400 614 Navi Mumbai (IN) (For All Designated States Except US).
SOHANI, Suhas, Vasant [IN/IN]; (IN) (For US Only).
KHOCHIKAR, Pravin , Gaj anan [IN/IN]; (IN) (For US Only).
TAMBOLI , Altaf , Abdul , Hamid [IN/IN]; (IN) (For US Only).
KULKARNI , Ramesh, Shankar [IN/IN]; (IN) (For US Only)
Inventors: SOHANI, Suhas, Vasant; (IN).
KHOCHIKAR, Pravin , Gaj anan; (IN).
TAMBOLI , Altaf , Abdul , Hamid; (IN).
KULKARNI , Ramesh, Shankar; (IN)
Agent: MAJUMDAR , Subhatosh; S . Majumdar & Co . 5 , Harish Mukherjee Road 700 025 Kolkata (IN)
Priority Data:
2022/MUM/2008 22.09.2008 IN
Title (EN) INDUSTRIAL PROCESS FOR CIS(+M-2-R(DIMETHYLAMINO)-METHYL-1-(3- METHOXYPHENYL) CYCLOHEXANOL HYDROCHLORIDE
(FR) PROCÉDÉ INDUSTRIEL POUR LA PRÉPARATION DE CIS(+M-2-R(DIMÉTHYLAMINO)-MÉTHYL-1-(3- MÉTHOXYPHÉNYL) CYCLOHEXANOL CHLORHYDRATE
Abstract: front page image
(EN)The present invention provides a process for the preparation of cis(+/-)-2- [(dimethylamino)-methyl]-1-(3-methoxyphenyl) cyclohexanol hydrochloride using the stable nitrate salt as an intermediate to give a product containing less than 0.2 % of the undesired "Trans" diastereomer.
(FR)La présente invention concerne un procédé pour la préparation de cis(+/-2- [diméthylamino)-méthyl]-1-(3- méthoxyphényl) cyclohexanol chlorhydrate utilisant le sel de nitrate stable comme intermédiaire pour obtenir un produit contenant moins de 0,2% de « Trans » diastéréomère indésirable.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)