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Machine translation
1. (WO2010032140) PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS OF DELIVERY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/032140    International Application No.:    PCT/IB2009/007155
Publication Date: 25.03.2010 International Filing Date: 17.09.2009
IPC:
A01N 65/00 (2009.01)
Applicants: CHIASMA INC. [IL/US]; 831 Beacon Street, Suite #313 Newton Centre, MA 02459 (US) (For All Designated States Except US).
SALAMA, Paul [IL/IL]; (IL) (NZ, US only).
MAMLUK, Roni [IL/IL]; (IL) (NZ, US only).
MAROM, Karen [IL/IL]; (IL) (NZ, US only).
WEINSTEIN, Irina [IL/IL]; (IL) (NZ, US only).
TZABARI, Moshe [IL/IL]; (IL) (NZ, US only)
Inventors: SALAMA, Paul; (IL).
MAMLUK, Roni; (IL).
MAROM, Karen; (IL).
WEINSTEIN, Irina; (IL).
TZABARI, Moshe; (IL)
Agent: McCARTY, Catherine, M.; Lando & Anastasi, LLP One main Street, Eleventh Floor Cambridge, MA 02142 (US)
Priority Data:
61/141,686 31.12.2008 US
61/097,716 17.09.2008 US
61/161,387 18.03.2009 US
Title (EN) PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS OF DELIVERY
(FR) PRÉPARATIONS PHARMACEUTIQUES ET MÉTHODES ASSOCIÉES D'ADMINISTRATION
Abstract: front page image
(EN)The pharmaceutical compositions described herein include a suspension which comprises an admixture in solid form of a therapeutically effective amount of a therapeutic agent and at least one salt of a medium chain fatty acid and a hydrophobic medium, e.g. castor oil or glyceryl tricaprylate or a mixture thereof. The pharmaceutical compositions described herein contain medium chain fatty acid salts and are substantially free of alcohols. The pharmaceutical compositions may be encapsulated in a capsule. Methods of treating or preventing diseases by administering such compositions to affected subjects are also disclosed.
(FR)Les préparations pharmaceutiques de l'invention comprennent une suspension faite d'un adjuvant sous forme solide comprenant une quantité thérapeutiquement efficace d'un agent thérapeutique et au moins un acide gras à chaîne médiane, et un milieu hydrophobe, par exemple de l'huile de ricin ou du tricaprylate de glycéryle ou leur mélange. Lesdites préparations pharmaceutiques: contiennent des sel d'acide gras à chaîne médiane, sont sensiblement exemptes d'alcools, et peuvent être encapsulées dans des capsules. L'invention porte également sur des méthodes de traitement et de prévention de maladies par administration de telles préparations à des sujets le nécessitant.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)