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1. (WO2010032059) ANTIBODIES DIRECTED TO CD105 AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/032059    International Application No.:    PCT/GB2009/051216
Publication Date: 25.03.2010 International Filing Date: 18.09.2009
IPC:
C07K 16/28 (2006.01), A61K 39/395 (2006.01)
Applicants: MEDIMMUNE LLC [US/US]; One MedImmune Way Gaithersburg, Maryland 20878 (US) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
MEDIMMUNE LIMITED [GB/GB]; Milstein Building Granta Park Cambridge Cambridgeshire CB21 6GH (GB) (MG only).
BABCOOK, John [CA/CA]; (CA) (For US Only).
BARRY, Simon, Thomas [GB/GB]; (GB) (For US Only).
GAZIT-BORNSTEIN, Gadi [US/US]; (US) (For US Only).
LAING, Naomi [CA/US]; (US) (For US Only).
ZHOU, Qing [US/US]; (US) (For US Only)
Inventors: BABCOOK, John; (CA).
BARRY, Simon, Thomas; (GB).
GAZIT-BORNSTEIN, Gadi; (US).
LAING, Naomi; (US).
ZHOU, Qing; (US)
Agent: ASTRAZENECA INTELLECTUAL PROPERTY; AstraZeneca AB S-SE-151 85 Södertälje (SE)
Priority Data:
61/098,685 19.09.2008 US
Title (EN) ANTIBODIES DIRECTED TO CD105 AND USES THEREOF
(FR) AGENTS DE LIAISON CIBLÉS DIRIGÉS SUR CD105 ET LEURS UTILISATIONS
Abstract: front page image
(EN)The invention relates to targeted binding agents against CD105 and uses of such agents. More specifically, the invention relates to fully human monoclonal antibodies directed to CD105. The described targeted binding agents are useful in the treatment of diseases associated with the activity and/or overproduction of CD105 and as diagnostics.
(FR)L'invention concerne des agents de liaison ciblés contre CD105 et l'utilisation de tels agents. De manière plus spécifique, l'invention concerne des anticorps monoclonaux totalement humains dirigés contre CD105. Les agents de liaison ciblés décrits sont utiles dans le traitement de maladies associées à l'activité et/ou la surproduction de CD105 et en tant qu'agents de diagnostic.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)