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Pub. No.:    WO/2010/032008    International Application No.:    PCT/GB2009/002219
Publication Date: 25.03.2010 International Filing Date: 16.09.2009
A61K 47/00 (2006.01), A61K 48/00 (2006.01), C07K 14/435 (2006.01), C07K 16/00 (2006.01), C12N 5/00 (2006.01), C12Q 1/00 (2006.01), A61P 31/00 (2006.01), A61P 35/00 (2006.01), A61P 37/02 (2006.01), A61P 29/00 (2006.01)
Applicants: NATURAL ENVIRONMENT RESEARCH COUNCIL [GB/GB]; Polaris House North Star Avenue Swindon SN2 1EU (GB) (For All Designated States Except US).
AUSTYN, Jon [GB/GB]; (GB) (For US Only).
PRESTON, Stephen [GB/GB]; (GB) (For US Only).
NUTTALL, Patricia [GB/GB]; (GB) (For US Only).
PAESEN, Guido [BE/GB]; (GB) (For US Only)
Inventors: AUSTYN, Jon; (GB).
PRESTON, Stephen; (GB).
NUTTALL, Patricia; (GB).
PAESEN, Guido; (GB)
Agent: ROQUES, Sarah, E.; J.A. Kemp & Co. 14 South Square Gray's Inn London WC1R 5LX (GB)
Priority Data:
0816976.5 16.09.2008 GB
Abstract: front page image
(EN)The present invention provides a dendritic cell modulatory molecule which modulates, and preferable inhibits, the differentiation and maturation of mammalian dendritic cells. The invention also provides pharmaceutical compositions comprising the dendritic cell modulatory molecule and homologues and active fragments thereof, antibodies thereto and methods of treatment and screening methods which utilise such molecules.
(FR)La présente invention concerne une molécule modulatrice des cellules dendritiques, qui se révèle capable de moduler et, de préférence, d'inhiber, la différentiation et la maturation des cellules dendritiques de mammifère. L'invention concerne également des compositions pharmaceutiques comprenant cette molécule modulatrice des cellules dendritiques, ainsi que des homologues et des fragments actifs de celle-ci, des anticorps dirigés contre celle-ci et des procédés de traitement et de criblage faisant appel auxdites molécules.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)