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Machine translation
1. (WO2010031978) SOX MODULATORS IN THE TREATMENT OF ALOPECIA
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/031978    International Application No.:    PCT/FR2009/051769
Publication Date: 25.03.2010 International Filing Date: 21.09.2009
IPC:
C12Q 1/68 (2006.01)
Applicants: GALDERMA RESEARCH & DEVELOPMENT [FR/FR]; 2400, route des Colles Les Templiers F-06410 Biot (FR) (For All Designated States Except US).
RETHORE, Sandrine [FR/FR]; (FR) (For US Only)
Inventors: RETHORE, Sandrine; (FR)
Agent: ANDRAL, Christophe; (FR)
Priority Data:
0856314 19.09.2008 FR
Title (EN) SOX MODULATORS IN THE TREATMENT OF ALOPECIA
(FR) MODULATEURS DE SOX DANS LE TRAITEMENT DE L'ALOPECIE
Abstract: front page image
(EN)The invention relates to an in vitro method for screening candidate compounds for the preventive or curative treatment of alopecia, said method comprising the determination of the capacity of a compound to modulate the expression or the activity of a SOX transcription factor, and the use of modulators of the expression or the activity of said transcription factor for the treatment of alopecia. The invention also relates to methods for the in vitro diagnosis or prognosis of said pathology
(FR)L'invention concerne une méthode in vitro de criblage de composés candidats pour le traitement préventif ou curatif de l'alopécie, comprenant la détermination de la capacité d'un composé à moduler l'expression ou l'activité d'un facteur de transcription SOX, ainsi que l'utilisation de modulateurs de l'expression ou de l'activité de ce facteur de transcription pour le traitement de l'alopécie. L'invention concerne aussi des méthodes de diagnostic ou pronostic in vitro de cette pathologie.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: French (FR)
Filing Language: French (FR)