WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2010031776) METHOD FOR PRODUCING L-PHENYLEPHRINE USING AN ALCOHOL DEHYDROGENASE OF AROMATOLEUM AROMATICUM EBN1 (AZOARCUS SP. EBN1)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/031776    International Application No.:    PCT/EP2009/061974
Publication Date: 25.03.2010 International Filing Date: 15.09.2009
IPC:
C12P 7/22 (2006.01), C12P 13/00 (2006.01)
Applicants: BASF SE [DE/DE]; 67056 Ludwigshafen (DE) (For All Designated States Except US).
BREUER, Michael [DE/DE]; (DE) (For US Only).
PLETSCH, Andreas [DE/DE]; (DE) (For US Only).
HAUER, Bernhard [DE/DE]; (DE) (For US Only).
SIEGEL, Wolfgang [DE/DE]; (DE) (For US Only)
Inventors: BREUER, Michael; (DE).
PLETSCH, Andreas; (DE).
HAUER, Bernhard; (DE).
SIEGEL, Wolfgang; (DE)
Agent: REITSTÖTTER KINZEBACH; Sternwartstr. 4 81679 München (DE)
Priority Data:
08164488.2 17.09.2008 EP
Title (DE) VERFAHREN ZUR HERSTELLUNG VON L-PHENYLEPHRIN UNTER VERWENDUNG EINER ALKOHOLDEHYDROGENASE AUS AROMATOLEUM AROMATICUM EBN1 (AZOARCUS SP. EBN1)
(EN) METHOD FOR PRODUCING L-PHENYLEPHRINE USING AN ALCOHOL DEHYDROGENASE OF AROMATOLEUM AROMATICUM EBN1 (AZOARCUS SP. EBN1)
(FR) PROCÉDÉ DE PRÉPARATION D'ALCOOLS OPTIQUEMENT ACTIFS
Abstract: front page image
(DE)Die vorliegende Erfindung betrifft ein mehrstufiges Verfahren zur Herstellung von substituierten, optisch aktiven Alkoholen, umfassend einen enzymkatalysierten, insbesondere von einer Alkoholdehydrogenase katalysierten Syntheseschritt. Insbesondere eignet sich das erfindungsgemässe Verfahren zur Herstellung von Phenylephrin, d.h. 3-[(1R)-1-Hydroxy-2-methylamino-ethyl]-phenol.
(EN)The present invention relates to a multi-stage process for producing substituted, optically active alcohols, comprising an enzyme-catalyzed synthesis step, in particular a synthesis step which is catalyzed by an alcohol dehydrogenase. The inventive method is particularly suitable for producing phenylephrine, i.e. 3-[(1R)-1-hydroxy-2-methylamino-ethyl]-phenol.
(FR)La présente invention concerne un procédé de préparation en plusieurs étapes d'alcools optiquement actifs substitués, comprenant une étape de synthèse catalysée par enzyme, en particulier par l'alcool déshydrogénase. Le procédé selon l'invention est adapté en particulier pour préparer de la phényléphrine, c.-à-d. du 3-[(1R)-1-hydroxy-2-méthylamino-éthyl]-phénol.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: German (DE)
Filing Language: German (DE)