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1. (WO2010031551) MONOCLONAL ANTIBODIES FOR TREATMENT OF CANCER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/031551    International Application No.:    PCT/EP2009/006704
Publication Date: 25.03.2010 International Filing Date: 16.09.2009
IPC:
C07K 16/30 (2006.01)
Applicants: GANYMED PHARMACEUTICALS AG [DE/DE]; Freiligrathstr. 12 55131 Mainz (DE) (For All Designated States Except US).
JOHANNES GUTENBERG-UNIVERSITÄT MAINZ [DE/DE]; Saarstrasse 21, 55122 Mainz (DE) (For All Designated States Except US).
SAHIN, Ugur [TR/DE]; (DE) (For US Only).
TÜRECI, Özlem [DE/DE]; (DE) (For US Only).
KOSLOWSKI, Michael [DE/DE]; (DE) (For US Only).
MITNACHT-KRAUS, Rita [DE/DE]; (DE) (For US Only)
Inventors: SAHIN, Ugur; (DE).
TÜRECI, Özlem; (DE).
KOSLOWSKI, Michael; (DE).
MITNACHT-KRAUS, Rita; (DE)
Agent: VOSSIUS, Volker; Geibelstrasse 6 81679 München (DE)
Priority Data:
08016277.9 16.09.2008 EP
61/097,453 16.09.2008 US
Title (EN) MONOCLONAL ANTIBODIES FOR TREATMENT OF CANCER
(FR) ANTICORPS MONOCLONAUX POUR LE TRAITEMENT DU CANCER
Abstract: front page image
(EN)The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing GT468, including tumor-related diseases such as breast Cancer, lung Cancer, gastric Cancer, ovarian Cancer, hepatocellular Cancer, colon Cancer, pancreatic Cancer, esophageal Cancer, head & neck Cancer, kidney Cancer, in particular renal cell Carcinoma, prostate Cancer, liver cancer, melanoma, sarcoma, myeloma, neuroblastoma, placental choriocarcinoma, cervical cancer, and thyroid Cancer, and the metastatic forms thereof. In one embodiment, the rumor disease is metastatic cancer in the lung.
(FR)La présente invention porte sur des anticorps utiles en tant que produits thérapeutiques pour traiter et/ou prévenir des maladies associées à des cellules exprimant GT468, comprenant des maladies tumorales telles que le cancer du sein, le cancer des poumons, le cancer de l'estomac, le cancer des ovaires, le cancer hépatocellulaire, le cancer du côlon, le cancer du pancréas, le cancer de l'œsophage, le cancer de la tête et du cou, le cancer du rein, en particulier l'hypernéphrome, le cancer de la prostate, le cancer du foie, un mélanome, un sarcome, un myélome, un neuroblastome, un chorio-épithéliome placentaire, le cancer du col de l'utérus et le cancer de la thyroïde, et leurs formes métastatiques. Dans un mode de réalisation, la maladie tumorale est un cancer métastatique dans le poumon.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)