WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2010030851) ALLEVIATING DISORDERS WITH COMBINING AGENTS THAT INCREASE EPOXYGENATED FATTY ACIDS AND AGENTS THAT INCREASE cAMP
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/030851    International Application No.:    PCT/US2009/056617
Publication Date: 18.03.2010 International Filing Date: 11.09.2009
IPC:
A01N 43/04 (2006.01), A61K 31/70 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street, 12 Floor Oakland, California 94607 (US) (For All Designated States Except US).
HAMMOCK, Bruce, D. [US/US]; (US) (For US Only).
INCEOGLU, A., Bora [TR/US]; (US) (For US Only).
JINKS, Steven, L. [US/US]; (US) (For US Only)
Inventors: HAMMOCK, Bruce, D.; (US).
INCEOGLU, A., Bora; (US).
JINKS, Steven, L.; (US)
Agent: WAHLSTEN, Jennifer, L.; Weaver Austin Villeneuve & Sampson LLP P.O. Box 70250 Oakland, CA 94612-0250 (US)
Priority Data:
61/097,141 15.09.2008 US
Title (EN) ALLEVIATING DISORDERS WITH COMBINING AGENTS THAT INCREASE EPOXYGENATED FATTY ACIDS AND AGENTS THAT INCREASE cAMP
(FR) SOULAGEMENT DE TROUBLES À L'AIDE D'AGENTS DE COMBINAISON QUI AUGMENTENT LES ACIDES GRAS ÉPOXYGÉNÉS ET D'AGENTS QUI AUGMENTENT LE MONOPHOSPHATE D'ADÉNOSINE CYCLIQUE
Abstract: front page image
(EN)The present invention relates to compositions and methods for promoting and enhancing the analgesic, anesthetic and anticonvulsant properties of epoxygenated fatty acids, in particular, epoxy-eicosatrienoic acids ("EETs") and inhibitors of soluble epoxide hydrolase ("sEH") in the presence of elevated levels of cyclic adenosine monophosphate ("cAMP") by combining or co-administering the epoxygenated fatty acid, EET and/or inhibitor of sEH with an agent that increases intracellular levels of cAMP, e.g., a phosphodiesterase inhibitor.
(FR)La présente invention porte sur des compositions et sur des méthodes pour favoriser et améliorer les propriétés analgésiques, anesthésiques et anticonvulsives d'acides gras époxygénés, en particulier des acides époxy-eicosatriénoïque (« EET ») et des inhibiteurs de l'hydrolase d'époxyde soluble (« sEH ») en présence de niveaux élevés de monophosphate d'adénosine cyclique (« cAMP ») par combinaison ou administration conjointe de l'acide gras époxygéné, du EET et/ou de l'inhibiteur de la sEH avec un agent qui augmente les niveaux intracellulaires de cAMP, par exemple un inhibiteur de la phosphodiestérase.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)