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Machine translation
1. (WO2010030395) WITHAFERIN A ANALOGS AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/030395    International Application No.:    PCT/US2009/005146
Publication Date: 18.03.2010 International Filing Date: 15.09.2009
IPC:
C07D 309/36 (2006.01), C07D 309/34 (2006.01), A61K 31/366 (2006.01), A61P 9/02 (2006.01), A61P 29/00 (2006.01)
Applicants: WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH [US/US]; Nine Cambridge Center Cambridge, MA 02142 (US) (For All Designated States Except US).
ARIZONA BOARD OF REGENTS on behalf of the UNIVERSITY OF ARIZONA [US/US]; 888 N. Euclid Avenue, Room 204 Tucson, AZ 85721-0158 (US) (For All Designated States Except US).
GUNATILAKA, Leslie [US/US]; (US) (For US Only).
WIJERATNE, Ekanayake Mudiyanselage Kithsiri [LK/US]; (US) (For US Only).
XU, Ya-Ming [CN/US]; (US) (For US Only).
WHITESELL, Luke J. [US/US]; (US) (For US Only).
LINDQUIST, Susan L. [US/US]; (US) (For US Only)
Inventors: GUNATILAKA, Leslie; (US).
WIJERATNE, Ekanayake Mudiyanselage Kithsiri; (US).
XU, Ya-Ming; (US).
WHITESELL, Luke J.; (US).
LINDQUIST, Susan L.; (US)
Agent: BAKER, C. Hunter; (US)
Priority Data:
61/097,088 15.09.2008 US
Title (EN) WITHAFERIN A ANALOGS AND USES THEREOF
(FR) ANALOGUES DE LA WITHAFÉRINE A ET LEURS UTILISATIONS
Abstract: front page image
(EN)The present invention provides a novel class of withanolides that have been isolated from W. somnifera under aeroponic conditions or produced semi-synthetically from withanolide natural products. The invention also provides pharmaceutical compositions thereof and methods for using the same in proliferative diseases, neurodegenerative diseases, autoimmune, and inflammatory diseases.
(FR)La présente invention concerne une nouvelle classe de withanolides qui ont été isolés à partir de W. somnifera dans des conditions aéroponiques ou produits de manière semi-synthétique à partir de produits naturels withanolides. L'invention concerne également des compositions pharmaceutiques de ceux-ci et leurs procédés d'utilisation dans des maladies prolifératives, des maladies neurodégénératives, auto-immunes, et des maladies inflammatoires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)