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1. (WO2010030343) BIOLUMINESCENT ASSAYS USING CYANOBENZOTHIAZOLE COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/030343    International Application No.:    PCT/US2009/005052
Publication Date: 18.03.2010 International Filing Date: 09.09.2009
IPC:
C07D 277/68 (2006.01), C12Q 1/25 (2006.01), C12Q 1/26 (2006.01), C12Q 1/34 (2006.01), C12Q 1/48 (2006.01), C12Q 1/66 (2006.01), G01N 21/76 (2006.01), C07K 5/10 (2006.01)
Applicants: PROMEGA CORPORATION [US/US]; 2800 Woods Hollow Road Madison, WI 53711 (US) (For All Designated States Except US).
ANDERSON, Jessica [US/US]; (US) (For US Only).
MEISENHEIMER, Poncho [US/US]; (US) (For US Only).
SHULTZ, John [US/US]; (US) (For US Only).
CALI, James, J. [US/US]; (US) (For US Only).
MA, Dongping [CA/US]; (US) (For US Only)
Inventors: ANDERSON, Jessica; (US).
MEISENHEIMER, Poncho; (US).
SHULTZ, John; (US).
CALI, James, J.; (US).
MA, Dongping; (US)
Agent: YAGER, Charlene, L.; (US)
Priority Data:
61/095,514 09.09.2008 US
Title (EN) BIOLUMINESCENT ASSAYS USING CYANOBENZOTHIAZOLE COMPOUNDS
(FR) DOSAGES BIOLUMINESCENTS AU MOYEN DE COMPOSÉS CYANOBENZOTHIAZOLE
Abstract: front page image
(EN)The invention provides methods that employ derivatives of 2-cyano-6-hydoxy- or 2-cyano-6-amino-benzothiazole, for example, in a bioluminogenic reaction. Also provided are novel compounds that can be used in the methods. The invention further provides methods for detecting or determining the presence of molecules and/or enzymes, the modulator activity of such molecules, and/or the activity of such enzymes. The methods are adaptable to high-throughput format.
(FR)Cette invention concerne des procédés qui utilisent des dérivés de 2-cyano-6-hydroxy- ou 2-cyano-6-amino-benzothiazole, par exemple, dans une réaction bioluminogène. De nouveaux composés qui peuvent être utilisés dans lesdits procédés sont également décrits. L'invention concerne, en outre, des procédés pour détecter ou déterminer la présence de molécules et/ou d'enzymes, l'activité modulatrice de ces molécules, et/ou l'activité de ces enzymes. Les procédés selon l'invention peuvent être adaptés au format haut débit.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)