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1. (WO2010029561) A PROCESS FOR PREPARATION OF ROSUVASTATIN ACETONIDE CALCIUM
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/029561    International Application No.:    PCT/IN2008/000696
Publication Date: 18.03.2010 International Filing Date: 22.10.2008
Chapter 2 Demand Filed:    25.03.2010    
IPC:
C07D 405/06 (2006.01), A61K 31/10 (2006.01), A61K 31/506 (2006.01), A61K 31/075 (2006.01), A61K 31/357 (2006.01), A61P 7/00 (2006.01)
Applicants: BIOCON LIMITED [IN/IN]; 20th KM, Hosur Road, Electronic City Bangalore 560 100 Karnataka (IN) (For All Designated States Except US).
SRINIVAS, Pullela, Venkata [IN/IN]; (IN) (For US Only).
ANEGONDI, Sreenivasa, Prasad [IN/IN]; (IN) (For US Only).
RAJMAHENDRA, Shanmughasamy [IN/IN]; (IN) (For US Only).
PONNUSAMY, Thangarasu [IN/IN]; (IN) (For US Only)
Inventors: SRINIVAS, Pullela, Venkata; (IN).
ANEGONDI, Sreenivasa, Prasad; (IN).
RAJMAHENDRA, Shanmughasamy; (IN).
PONNUSAMY, Thangarasu; (IN)
Agent: GUPTA, Maram, Suresh; K & S Partners 4121/B, 6th Cross, 19A Main Hal II Stage (Extension) Bangalore 560 038 Karnataka (IN)
Priority Data:
02187/CHE/2008 09.09.2008 IN
Title (EN) A PROCESS FOR PREPARATION OF ROSUVASTATIN ACETONIDE CALCIUM
(FR) PROCÉDÉ DE PRÉPARATION D’ACÉTONIDE DE ROSUVASTATINE CALCIQUE
Abstract: front page image
(EN)The present invention is in relation to a process for preparation of HMG-CoA reductase inhibitor. More particularly, the present invention provides a process for preparation of (3R,5S,6E) 6-{2-[4-(4-Fluoro-phenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl]-vinyl}-2,2-dimethyl-[1,3]dioxan-4-yl)-acetic acid,calcium salt (Rosuvastatin acetonide calcium) which is used for treating hypercholesterolemia.
(FR)La présente invention concerne un procédé de préparation d’un inhibiteur de la HMG-CoA réductase. L’invention concerne plus particulièrement un procédé de préparation du sel de calcium de l’acide (3R,5S,6E)-6-{2-[4-(4-fluoro-phényl)-6-isopropyl-2-(méthanesulfonyl-méthyl-amino)-pyrimidin-5-yl]-vinyl}-2,2-diméthyl-[1,3]dioxan-4-yl)-acétique (acétonide de Rosuvastatine calcique) qui est utilisé pour traiter l’hypercholestérolémie.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)