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Machine translation
1. (WO2010029436) NOVEL SOLID STATE FORMS OF RANOLAZINE SALTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/029436    International Application No.:    PCT/IB2009/006948
Publication Date: 18.03.2010 International Filing Date: 08.09.2009
IPC:
C07D 295/14 (2006.01), C07D 295/088 (2006.01), A61K 31/495 (2006.01), A61P 9/10 (2006.01)
Applicants: ACTAVIS GROUP PTC EHF [IS/IS]; Reykjavikurvegi 76-78 IS-220 Hafnarfjörour (IS) (For All Designated States Except US).
ATHUKURI, Venkata, Subbarao [IN/IN]; (IN) (For US Only).
SWAMY, Saidugari [IN/IN]; (IN) (For US Only).
KHUNT, Mayur, Devjibhai [IN/IN]; (IN) (For US Only).
PRADHAN, Nitin, Sharadchandra [IN/IN]; (IN) (For US Only)
Inventors: ATHUKURI, Venkata, Subbarao; (IN).
SWAMY, Saidugari; (IN).
KHUNT, Mayur, Devjibhai; (IN).
PRADHAN, Nitin, Sharadchandra; (IN)
Priority Data:
2185/CHE/2008 09.09.2008 IN
Title (EN) NOVEL SOLID STATE FORMS OF RANOLAZINE SALTS
(FR) NOUVELLES FORMES SOLIDES DE SELS DE RANOLAZINE
Abstract: front page image
(EN)Provided herein are solid state forms of ranolazine salts. Also provided is a stable amorphous form of ranolazine hydrochloride having a water content of less than about 0.5% by weight. Further provided are amorphous co-precipitates of ranolazine or a pharmaceutically acceptable salt thereof with povidone. Processes for the preparation of ranolazine forms, pharmaceutical compositions, and methods of treating thereof are also included. The solid state forms of ranolazine salts are useful for preparing ranolazine in high purity.
(FR)L'invention concerne des formes solides de sels de ranolazine. L'invention concerne également une forme amorphe stable d'hydrochlorure de ranolazine qui a une teneur en eau inférieure à environ 0,5 % en poids. L'invention concerne également des co-précipités amorphes de ranolazine ou d'un de ses sels pharmaceutiquement acceptables avec de la povidone. L'invention concerne également des procédés de préparation de formes de ranolazine, des compositions pharmaceutiques et leurs procédés de traitement. Les formes solides de sels de ranolazine sont utiles pour préparer de la ranolazine avec une grande pureté.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)