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1. (WO2010029178) FACTOR IX POLYPEPTIDE MUTANT, ITS USES AND A METHOD FOR ITS PRODUCTION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/029178    International Application No.:    PCT/EP2009/061935
Publication Date: 18.03.2010 International Filing Date: 15.09.2009
Chapter 2 Demand Filed:    14.07.2010    
IPC:
C12N 9/64 (2006.01), C12N 15/57 (2006.01), A61K 38/48 (2006.01)
Applicants: SIMIONI, Paolo [IT/IT]; (IT)
Inventors: SIMIONI, Paolo; (IT)
Agent: GERVASI, Gemma; Notarbartolo & Gervasi S.p.A. Corso di Porta Vittoria, 9 I-20122 Milan (IT)
Priority Data:
BO2008A000564 15.09.2008 IT
BO2009A000275 06.05.2009 IT
Title (EN) FACTOR IX POLYPEPTIDE MUTANT, ITS USES AND A METHOD FOR ITS PRODUCTION
(FR) MUTANT POLYPEPTIDIQUE DU FACTEUR IX, SES UTILISATIONS ET MÉTHODE POUR SA PRODUCTION
Abstract: front page image
(EN)Disclosed are a modified FIX (factor IX) polypeptide comprising a leucine, cysteine, aspartic acid, glutamic acid, histidine, lysine, asparagine, glutamine or tyrosine in position 338; pharmaceutical preparations containing said modified FIX polypeptide; a nucleotide sequence coding for the modified FIX polypeptide; and a method for producing the modified FIX polypeptide.
(FR)L'invention porte sur un polypeptide FIX (facteur IX) modifié comprenant une leucine, une cystéine, un acide aspartique, un acide glutamique, une histidine, une lysine, une asparagine, une glutamine ou une tyrosine en position 338; sur des préparations pharmaceutiques contenant ledit polypeptide FIX modifié; sur une séquence nucléotidique codante pour le polypeptide FIX modifié; et sur une méthode pour la fabrication du polypeptide FIX modifié.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)