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67. (WO2010029174) METHOD FOR CLASSIFYING A CANCER PATIENT AS RESPONDER OR NON-RESPONDER TO IMMUNOTHERAPY
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2010/029174 International Application No.: PCT/EP2009/061888
Publication Date: 18.03.2010 International Filing Date: 14.09.2009
IPC:
C12Q 1/68 (2006.01)
[IPC code unknown for C12Q 1/68]
Applicants:
DUPONT, Pierre, Raphael [BE/BE]; BE (UsOnly)
GAULIS, Swann, Romain, Jean-Thomas [FR/BE]; BE (UsOnly)
HELLEPUTTE, Thibault, Marc [BE/BE]; BE (UsOnly)
GLAXOSMITHKLINE BIOLOGICALS S.A. [BE/BE]; Rue de l'Institut 89 B-1330 Rixensart, BE (AllExceptUS)
Inventors:
DUPONT, Pierre, Raphael; BE
GAULIS, Swann, Romain, Jean-Thomas; BE
HELLEPUTTE, Thibault, Marc; BE
Agent:
LOVATT, Victoria, Jayne; GB
Priority Data:
0816867.615.09.2008GB
61/192,04215.09.2008US
Title (EN) METHOD FOR CLASSIFYING A CANCER PATIENT AS RESPONDER OR NON-RESPONDER TO IMMUNOTHERAPY
(FR) MÉTHODE
Abstract:
(EN) Gene expression profiles, microarrays comprising nucleic acid sequences representing gene expression profiles, and new diagnostic kits and methods are provided. The kits and methods relate to the treatment of specific populations of, for example, cancer patients, as characterised by their gene expression profile, suffering from MAGE expressing tumours. A 33 gene expression signature identifies melanoma patients responding to treatment with MAGE-A3 ASCI.
(FR) L'invention porte sur des profils d'expression génique, des microréseaux comprenant des séquences d'acides nucléiques représentant des profils d'expression génique, et sur de nouveaux kits de diagnostic ainsi que sur des méthodes. Les kits et procédés portent sur le traitement de populations spécifiques, par exemple, de patients cancéreux, tels que caractérisés par leur profil d'expression génique, souffrant de tumeurs exprimant MAGE.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)