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1. (WO2010028999) PRODUCTION OF INFECTIOUS HEPATITIS C VIRUS PARTICLES IN CELL CULTURE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/028999    International Application No.:    PCT/EP2009/061363
Publication Date: 18.03.2010 International Filing Date: 03.09.2009
Chapter 2 Demand Filed:    26.02.2010    
IPC:
C12N 7/02 (2006.01), C12Q 1/70 (2006.01), C07K 14/18 (2006.01)
Applicants: F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124 CH-4070 Basel (CH) (For All Designated States Except US).
MCCOWN, Matthew [US/US]; (US) (For US Only).
NAJERA, Isabel [GB/US]; (US) (For US Only)
Inventors: MCCOWN, Matthew; (US).
NAJERA, Isabel; (US)
Agent: KJELLSAA-BERGER, Hanny; Grenzacherstrasse 124 CH-4070 Basel (CH)
Priority Data:
61/191,862 12.09.2008 US
Title (EN) PRODUCTION OF INFECTIOUS HEPATITIS C VIRUS PARTICLES IN CELL CULTURE
(FR) PRODUCTION DE PARTICULES DE VIRUS DE L’HÉPATITE C INFECTIEUSES EN CULTURE DE CELLULES
Abstract: front page image
(EN)The present invention provides for novel methods of producing high levels of infectious HCV genotype 1 virus particles in cell culture systems. The availability of HCV genotype 1 virus (principally associated with liver disease in most regions of the world) that can undergo the complete viral cycle in cultured cells is beneficial for the discovery and development of novel therapies for the treatment of HCV.
(FR)La présente invention concerne de nouveaux procédés de production de taux élevés de particules de virus VHC de génotype 1 infectieuses dans des systèmes de culture de cellules. La disponibilité du virus VHC de génotype 1 (principalement associé à une maladie hépatique dans la plupart des régions du monde) qui peut subir le cycle viral complet dans des cellules en culture est bénéfique pour la découverte et le développement de nouvelles thérapies pour le traitement du VHC.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)