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Machine translation
1. (WO2010028846) TREATMENT OF ACUTE MYOCARDIAL INFARCTION (AMI) USING ENCAPSULATED CELLS ENCODING AND SECRETING GLP-1 PEPTIDES OR ANALOGS THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/028846    International Application No.:    PCT/EP2009/006620
Publication Date: 18.03.2010 International Filing Date: 11.09.2009
IPC:
A61K 9/50 (2006.01), C12N 5/00 (2006.01), A61P 9/00 (2006.01)
Applicants: BIOCOMPATIBLES UK LTD. [GB/GB]; Chapman House Farnham Business Park Weydon Lane, Farnham Surrey GU9 8QL (GB) (For All Designated States Except US).
WALLRAPP, Christine [DE/DE]; (DE) (For US Only).
LEWIS, Andrew Lennhard [GB/GB]; (GB) (For US Only).
STRATFORD, Peter William [GB/GB]; (GB) (For US Only).
THOENES, Eric [DE/DE]; (DE) (For US Only)
Inventors: WALLRAPP, Christine; (DE).
LEWIS, Andrew Lennhard; (GB).
STRATFORD, Peter William; (GB).
THOENES, Eric; (DE)
Agent: GRINDL, Wolfgang; GRAF VON STOSCH PATENTANWALTSGESELLSCHAFT MBH Prinzregentenstrasse 22 80538 München (DE)
Priority Data:
08016137.5 12.09.2008 EP
Title (EN) TREATMENT OF ACUTE MYOCARDIAL INFARCTION (AMI) USING ENCAPSULATED CELLS ENCODING AND SECRETING GLP-1 PEPTIDES OR ANALOGS THEREOF
(FR) TRAITEMENT DE L'INFARCTUS AIGU DU MYOCARDE (IAM) À L'AIDE DE CELLULES ENCAPSULÉES CODANT ET SÉCRÉTANT DES PEPTIDES GLP-1 OU DES ANALOGUES DE CEUX-CI
Abstract: front page image
(EN)The present application refers to the use of cells, e.g. mesenchymal stem cells or mesenchymal stromal cells, or any further suitable cell, encoding and secreting GLP-1, a fragment or variant thereof or a fusion peptide comprising GLP-1 or a fragment or variant thereof, for the treatment of acute myocardial infarction (AMI or Ml), wherein the cells, encoding and secreting GLP-1, a fragment or variant thereof or a fusion peptide comprising GLP-1 or a fragment or variant thereof, are encapsulated in a (spherical) microcapsule to prevent a response of the immune system of the patient to be treated. The present application also refers to the use of these (spherical) microcapsule(s) or of a pharmaceutical composition containing these cells or (spherical) microcapsule(s) for the treatment of acute myocardial infarction (AMI or Ml).
(FR)
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)