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1. (WO2010028798) MULTIVALENT ANTIBODIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/028798    International Application No.:    PCT/EP2009/006500
Publication Date: 18.03.2010 International Filing Date: 08.09.2009
IPC:
C07K 16/28 (2006.01), A61P 31/18 (2006.01), A61K 47/48 (2006.01), A61K 39/395 (2006.01), A61K 39/42 (2006.01)
Applicants: ROCHE GLYCART AG [CH/CH]; Wagistrasse 18 CH-8952 Schlieren (CH) (For All Designated States Except US).
AUER, Johannes [DE/DE]; (DE) (For US Only).
BRANDT, Michael [DE/DE]; (DE) (For US Only).
BRINKMANN, Ulrich [DE/DE]; (DE) (For US Only).
DORMEYER, Wilma [DE/DE]; (DE) (For US Only).
HOFFMANN, Eike [DE/DE]; (DE) (For US Only).
JEKLE, Andreas [DE/US]; (US) (For US Only).
NEZU, Jun-ichi [JP/JP]; (JP) (For US Only).
SCHANZER, Juergen Michael [DE/DE]; (DE) (For US Only).
STRACKE, Jan Olaf [DE/DE]; (DE) (For US Only).
UMANA, Pablo [CR/CH]; (CH) (For US Only)
Inventors: AUER, Johannes; (DE).
BRANDT, Michael; (DE).
BRINKMANN, Ulrich; (DE).
DORMEYER, Wilma; (DE).
HOFFMANN, Eike; (DE).
JEKLE, Andreas; (US).
NEZU, Jun-ichi; (JP).
SCHANZER, Juergen Michael; (DE).
STRACKE, Jan Olaf; (DE).
UMANA, Pablo; (CH)
Agent: BURGER, Alexander; Roche Diagnostics GmbH Patent Department (TR-E) Postfach 11 52 82372 Penzberg (DE)
Priority Data:
08015910.6 10.09.2008 EP
Title (EN) MULTIVALENT ANTIBODIES
(FR) ANTICORPS MULTIVALENTS
Abstract: front page image
(EN)Herein is reported an antibody, characterized in that said antibody comprises four antigen-binding sites each consisting of a pair of antibody variable domains, whereby each of said antigen-binding sites bind to the same epitope.
(FR)Cette invention concerne un anticorps, caractérisé en ce que ledit anticorps comprend quatre sites de liaison à l'antigène, constitués chacun par une paire de domaines variables d'anticorps, chacun desdits sites de liaison à l'antigène se liant au même épitope.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)