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1. (WO2010028160) METHODS FOR THE DETECTION OF CIRCULATING TUMOR CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/028160    International Application No.:    PCT/US2009/055906
Publication Date: 11.03.2010 International Filing Date: 03.09.2009
IPC:
G01N 33/574 (2006.01)
Applicants: THE SCRIPPS RESEARCH INSTITUTE [US/US]; 10550 North Torrey Pines Road La Jolla, CA 92037 (US) (For All Designated States Except US).
KUHN, Peter [US/US]; (US) (For US Only).
GRIFFIN, John [US/US]; (US) (For US Only).
BETHEL, Kelly [US/US]; (US) (For US Only).
MARRINUCCI, Dena [US/US]; (US) (For US Only)
Inventors: KUHN, Peter; (US).
GRIFFIN, John; (US).
BETHEL, Kelly; (US).
MARRINUCCI, Dena; (US)
Agent: HAILE, Lisa, A.; (US)
Priority Data:
61/094,819 05.09.2008 US
Title (EN) METHODS FOR THE DETECTION OF CIRCULATING TUMOR CELLS
(FR) MÉTHODES DE DÉTECTION DE CELLULES TUMORALES CIRCULANTES
Abstract: front page image
(EN)The present invention provides methods for revealing, detecting, and analyzing circulating tumor cells in the blood of a subject. Revealing detectable circulating tumor cells allows for early stage detection and diagnosis in addition to long term prognosis in subjects with cancer. Additionally, enrichment allows for robust detection and clinically meaningful analysis of low volume samples for use in clinical settings as well as innovative methods for the treatment of cancers.
(FR)La présente invention porte sur des méthodes permettant de révéler, détecter et analyser des cellules tumorales circulantes dans le sang d'un sujet. La révélation de cellules tumorales circulantes détectables permet une détection de stade précoce et un diagnostic en plus d'un pronostic à long terme sur des sujets atteints de cancer. De plus, un enrichissement permet une détection robuste et une analyse cliniquement significative d'échantillons de petit volume destinés à être utilisés dans des environnements cliniques ainsi que sur des méthodes innovantes de traitement de cancers.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)