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1. WO2010028133 - IMAGING NEUROLEPTIC COMPOUNDS

Publication Number WO/2010/028133
Publication Date 11.03.2010
International Application No. PCT/US2009/055869
International Filing Date 03.09.2009
IPC
A61K 31/445 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
445Non-condensed piperidines, e.g. piperocaine
CPC
A61K 31/445
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non condensed pyridines; Hydrogenated derivatives thereof
445Non condensed piperidines, e.g. piperocaine
G01N 2800/302
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2800Detection or diagnosis of diseases
30Psychoses; Psychiatry
302Schizophrenia
G01N 33/5088
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
5005involving human or animal cells
5008for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
5082Supracellular entities, e.g. tissue, organisms
5088of vertebrates
Applicants
  • NORTHEASTERN UNIVERSITY [US]/[US] (AllExceptUS)
  • FERRIS, Craig [US]/[US] (UsOnly)
Inventors
  • FERRIS, Craig
Agents
  • KERNER, Ann-Louise
Priority Data
61/093,90803.09.2008US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) IMAGING NEUROLEPTIC COMPOUNDS
(FR) IMAGERIE DE COMPOSÉS NEUROLEPTIQUES
Abstract
(EN) A method for identifying typical and atypical antipsychotics based on their ability to reduce neuronal/glial activity in specific brain regions upon dopaminergic neurotransmission is disclosed.
(FR) L'invention porte sur un procédé d'identification d'antipsychotiques typiques et atypiques sur la base de leur aptitude à réduire l'activité neuronale/gliale dans des régions cérébrales spécifiques lors d'une neurotransmission dopaminergique.
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