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Machine translation
1. (WO2010028125) METHOD FOR DETECTION OF CANCER BASED ON SPATIAL GENOME ORGANIZATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/028125    International Application No.:    PCT/US2009/055857
Publication Date: 11.03.2010 International Filing Date: 03.09.2009
IPC:
C12Q 1/68 (2006.01)
Applicants: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES [US/US]; Office of Technology Transfer National Institutes of Health 6011 Executive Boulevard, Suite 325 MSC 7660 Bethesda, Maryland 20892-7660 (US) (For All Designated States Except US).
MISTELI, Thomas A. [CH/US]; (US) (For US Only).
MEABURN, Karen [GB/US]; (US) (For US Only)
Inventors: MISTELI, Thomas A.; (US).
MEABURN, Karen; (US)
Agent: JAY, Jeremy, M.; LEYDIG, VOIT & MAYER Two Prudential Plaza, Suite 490 180 N. Stetson Avenue Chicago, Illinois 60601 (US)
Priority Data:
61/094,318 04.09.2008 US
Title (EN) METHOD FOR DETECTION OF CANCER BASED ON SPATIAL GENOME ORGANIZATION
(FR) PROCÉDÉ DE DÉTECTION D'UN CANCER SUR LA BASE D'UNE ORGANISATION SPATIALE DU GÉNOME SPATIAL
Abstract: front page image
(EN)The invention provides methods of detecting abnormal cells in a sample using the radial position of one or more genes within the nucleus of a cell, as well as a kit for detecting abnormal cells using such methods. The invention also provides methods of identifying gene markers for abnormal cells using the radial position of one or more genes within the nucleus of a cell.
(FR)L'invention porte sur des procédés de détection de cellules anormales dans un échantillon à l'aide de la position radiale d'un ou plusieurs gènes à l'intérieur du noyau d'une cellule, ainsi que sur un kit pour détecter des cellules anormales à l'aide de tels procédés. L'invention porte également sur des procédés d'identification de marqueurs géniques pour des cellules anormales à l'aide de la position radiale d'un ou plusieurs gènes dans le noyau d'une cellule.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)